Enhancement of the Antitumor Effect of γ-Ray Irradiation in Combination with Camptothecin against Human Colorectal Adenocarcinoma

The effect of γ-ray irradiation and camptothecin (CAM) on human colorectal adenocarcinoma (LS 174T) growth was examined. On inhibition of DNA synthesis of LS 174T cells, almost all combined treatments presented a synergistic effect, excepting that the additive effects were shown at the lowest or the...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 1996/03/15, Vol.19(3), pp.354-359
Hauptverfasser:	WANG, Dian-Sheng, UENO, Yoshio, OYAMADA, Hiyoshimaru, KOJIMA, Shuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - radiotherapy Adenocarcinoma - therapy Animals Antibodies, Monoclonal - therapeutic use Antineoplastic Agents, Phytogenic - therapeutic use camptothecin Camptothecin - therapeutic use Carcinoembryonic Antigen - immunology Colorectal Neoplasms - drug therapy Colorectal Neoplasms - radiotherapy Colorectal Neoplasms - therapy combination-radioimmunotherapy Combined Modality Therapy Gamma Rays human colorectal adenocarcinoma Humans Iodine Radioisotopes Mice Mice, Nude NCC-CO-411 MoAb Neoplasm Transplantation Radioimmunotherapy Transplantation, Heterologous
Online-Zugang:	Volltext
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