Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion

Reperfusion of ischemic tissue is responsible for production of metabolites with deleterious local vascular effects. Thromboxane A 2, a potent vasoconstrictor and platelet aggregator, has been implicated as a mediator of the “reperfusion injury.” We studied the effect of an experimental thromboxane...

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