A Comparison of the DNA and Chromosome Repair Kinetics after γ Irradiation

The kinetics of repair at the chromosome and DNA levels were compared after γ irradiation of Chinese hamster ovary cells (CHO). Induction and repair of DNA damage were measured by the alkaline and neutral elution techniques, while chromosome damage and repair were determined by the technique of prem...

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Veröffentlicht in:	Radiat. Res.; (United States) 1982-12, Vol.92 (3), p.497-509
Hauptverfasser:	Hittelman, Walter N., Pollard, Margaret
Format:	Artikel
Sprache:	eng
Schlagworte:	560121 - Radiation Effects on Cells- External Source- (-1987) ANIMAL CELLS ANIMALS ANTI-INFECTIVE AGENTS ANTIBIOTICS BIOLOGICAL EFFECTS BIOLOGICAL RADIATION EFFECTS BIOLOGICAL RECOVERY BIOLOGICAL REPAIR Cell Line CHO cells Chromosome Aberrations CHROMOSOMES CONNECTIVE TISSUE CELLS Cricetinae Cricetulus CYCLOHEXIMIDE Cycloheximide - pharmacology Diphosphates - pharmacology DNA DNA damage DNA repair DNA Repair - drug effects DRUGS Edetic Acid - pharmacology ELECTROMAGNETIC RADIATION Elution Female FIBROBLASTS FUNGICIDES GAMMA RADIATION Gamma Rays HAMSTERS IONIZING RADIATIONS Irradiation KINETICS Lesions MAMMALS NUCLEIC ACIDS ORGANIC COMPOUNDS Ovary PESTICIDES Radiation damage RADIATION EFFECTS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIATIONS RADIOINDUCTION RECOVERY REPAIR RODENTS Sister Chromatid Exchange SOMATIC CELLS Space life sciences STRAND BREAKS Time Factors VERTEBRATES
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