Effects of infusion of cholinergic drugs into the prefrontal cortex area on delayed matching to position performance in the rat

Rats trained on a Delayed Matching To Position (DMTP) task displayed mediating behavior during delays to solve the task. Infusion of the cholinergic antagonist scopolamine into the medial Prefrontal Cortex area (mPFC), dose dependently impaired performance independent of delay. These results indicat...

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Veröffentlicht in:	Brain research 1996-03, Vol.711 (1), p.102-111
Hauptverfasser:	Herremans, Arnoud H.J., Hijzen, Theo H., Welborn, Patrick F.E., Olivier, Berend, Slangen, Jef L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Behavioral psychophysiology Biological and medical sciences Cholinergic system Delayed Matching to Position Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Male Neurotransmission and behavior Parasympatholytics - pharmacology Pirenzepine - analogs & derivatives Pirenzepine - pharmacology Prefrontal cortex Prefrontal Cortex - drug effects Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rat Rats Rats, Wistar Scopolamine Scopolamine - pharmacology Selective attention Time Factors Working memory
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