Dissemination of disease following transurethral resection for locally advanced prostate cancer
Between 1974 and 1978, 258 patients with clinical Stage C adenocarcinoma of the prostate were treated at the U. T. M.D. Anderson Hospital in Houston. Of these, 208 were considered evaluable for a review of the impact of transurethral resection (TUR) on the dissemination of disease. After TUR, the in...
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Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 1988, Vol.31 (1), p.30-33 |
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description | Between 1974 and 1978, 258 patients with clinical Stage C adenocarcinoma of the prostate were treated at the U. T. M.D. Anderson Hospital in Houston. Of these, 208 were considered evaluable for a review of the impact of transurethral resection (TUR) on the dissemination of disease. After TUR, the incidence of disease progression was 38.9 per cent, compared with 36.4 per cent for patients who did not undergo TUR. There were significant differences in both incidence of progression (31.2 % versus 55.6 %, p = 0.002) and time to progression (p < 0.001) when patients were divided into Stages C1 and C2 (presence or absence of pelvic side wall fixation) irrespective of their TUR status. Therefore, it appears that for patients with locally advanced prostate cancer, the degree of tumor burden and not the TUR status has a significant influence on disease progression. |
doi_str_mv | 10.1016/0090-4295(88)90567-5 |
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T. M.D. Anderson Hospital in Houston. Of these, 208 were considered evaluable for a review of the impact of transurethral resection (TUR) on the dissemination of disease. After TUR, the incidence of disease progression was 38.9 per cent, compared with 36.4 per cent for patients who did not undergo TUR. There were significant differences in both incidence of progression (31.2 % versus 55.6 %, p = 0.002) and time to progression (p < 0.001) when patients were divided into Stages C1 and C2 (presence or absence of pelvic side wall fixation) irrespective of their TUR status. Therefore, it appears that for patients with locally advanced prostate cancer, the degree of tumor burden and not the TUR status has a significant influence on disease progression.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/0090-4295(88)90567-5</identifier><identifier>PMID: 3122398</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Actuarial Analysis ; Adenocarcinoma - radiotherapy ; Adenocarcinoma - secondary ; Adenocarcinoma - surgery ; Aged ; Aged, 80 and over ; Combined Modality Therapy ; Humans ; Lymph Node Excision ; Male ; Middle Aged ; Prognosis ; Prostatectomy ; Prostatic Neoplasms - radiotherapy ; Prostatic Neoplasms - surgery ; Radiotherapy, High-Energy ; Retrospective Studies</subject><ispartof>Urology (Ridgewood, N.J.), 1988, Vol.31 (1), p.30-33</ispartof><rights>1988</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c272t-8074b667e521bea4eb9df3c1baaad25d0fdbaa471701d40f8e95985dc739322c3</citedby><cites>FETCH-LOGICAL-c272t-8074b667e521bea4eb9df3c1baaad25d0fdbaa471701d40f8e95985dc739322c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0090429588905675$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3122398$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Babaian, R.Joseph</creatorcontrib><creatorcontrib>Archer, J.Steven</creatorcontrib><title>Dissemination of disease following transurethral resection for locally advanced prostate cancer</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>Between 1974 and 1978, 258 patients with clinical Stage C adenocarcinoma of the prostate were treated at the U. 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Therefore, it appears that for patients with locally advanced prostate cancer, the degree of tumor burden and not the TUR status has a significant influence on disease progression.</description><subject>Actuarial Analysis</subject><subject>Adenocarcinoma - radiotherapy</subject><subject>Adenocarcinoma - secondary</subject><subject>Adenocarcinoma - surgery</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Combined Modality Therapy</subject><subject>Humans</subject><subject>Lymph Node Excision</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Prostatectomy</subject><subject>Prostatic Neoplasms - radiotherapy</subject><subject>Prostatic Neoplasms - surgery</subject><subject>Radiotherapy, High-Energy</subject><subject>Retrospective Studies</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1PBCEMhonR6PrxDzThZPQwCswwwMXErJ-JiRc9EwY6imEHhVmN_17G3Xj01DZ927d9EDqk5IwS2p4TokjVMMVPpDxVhLei4htoRjkTlVKKb6LZn2QH7eb8Rghp21Zso-2aMlYrOUP6yucMCz-Y0ccBxx47n8FkwH0MIX754QWPyQx5mWB8TSbgBBnsr7iPCYdoTQjf2LhPM1hw-D3FPJoRsJ3qtI-2ehMyHKzjHnq-uX6a31UPj7f388uHyjLBxkoS0XTlNOCMdmAa6JTra0s7Y4xj3JHelbQRVBDqGtJLUFxJ7qyoVc2YrffQ8Wpv8f9YQh71wmcLIZgB4jJrIYlsqWqLsFkJbTk0J-j1e_ILk741JXriqidoeoKmpdS_XDUvY0fr_ctuAe5vaA2y9C9WfShPfnpIOlsPExGfCi7tov_f4AfRuYmo</recordid><startdate>1988</startdate><enddate>1988</enddate><creator>Babaian, R.Joseph</creator><creator>Archer, J.Steven</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1988</creationdate><title>Dissemination of disease following transurethral resection for locally advanced prostate cancer</title><author>Babaian, R.Joseph ; Archer, J.Steven</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c272t-8074b667e521bea4eb9df3c1baaad25d0fdbaa471701d40f8e95985dc739322c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Actuarial Analysis</topic><topic>Adenocarcinoma - radiotherapy</topic><topic>Adenocarcinoma - secondary</topic><topic>Adenocarcinoma - surgery</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Combined Modality Therapy</topic><topic>Humans</topic><topic>Lymph Node Excision</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Prostatectomy</topic><topic>Prostatic Neoplasms - radiotherapy</topic><topic>Prostatic Neoplasms - surgery</topic><topic>Radiotherapy, High-Energy</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Babaian, R.Joseph</creatorcontrib><creatorcontrib>Archer, J.Steven</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Babaian, R.Joseph</au><au>Archer, J.Steven</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dissemination of disease following transurethral resection for locally advanced prostate cancer</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>1988</date><risdate>1988</risdate><volume>31</volume><issue>1</issue><spage>30</spage><epage>33</epage><pages>30-33</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><abstract>Between 1974 and 1978, 258 patients with clinical Stage C adenocarcinoma of the prostate were treated at the U. 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subjects | Actuarial Analysis Adenocarcinoma - radiotherapy Adenocarcinoma - secondary Adenocarcinoma - surgery Aged Aged, 80 and over Combined Modality Therapy Humans Lymph Node Excision Male Middle Aged Prognosis Prostatectomy Prostatic Neoplasms - radiotherapy Prostatic Neoplasms - surgery Radiotherapy, High-Energy Retrospective Studies |
title | Dissemination of disease following transurethral resection for locally advanced prostate cancer |
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