Dissemination of disease following transurethral resection for locally advanced prostate cancer

Between 1974 and 1978, 258 patients with clinical Stage C adenocarcinoma of the prostate were treated at the U. T. M.D. Anderson Hospital in Houston. Of these, 208 were considered evaluable for a review of the impact of transurethral resection (TUR) on the dissemination of disease. After TUR, the in...

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Veröffentlicht in:Urology (Ridgewood, N.J.) N.J.), 1988, Vol.31 (1), p.30-33
Hauptverfasser: Babaian, R.Joseph, Archer, J.Steven
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description Between 1974 and 1978, 258 patients with clinical Stage C adenocarcinoma of the prostate were treated at the U. T. M.D. Anderson Hospital in Houston. Of these, 208 were considered evaluable for a review of the impact of transurethral resection (TUR) on the dissemination of disease. After TUR, the incidence of disease progression was 38.9 per cent, compared with 36.4 per cent for patients who did not undergo TUR. There were significant differences in both incidence of progression (31.2 % versus 55.6 %, p = 0.002) and time to progression (p < 0.001) when patients were divided into Stages C1 and C2 (presence or absence of pelvic side wall fixation) irrespective of their TUR status. Therefore, it appears that for patients with locally advanced prostate cancer, the degree of tumor burden and not the TUR status has a significant influence on disease progression.
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T. M.D. Anderson Hospital in Houston. Of these, 208 were considered evaluable for a review of the impact of transurethral resection (TUR) on the dissemination of disease. After TUR, the incidence of disease progression was 38.9 per cent, compared with 36.4 per cent for patients who did not undergo TUR. There were significant differences in both incidence of progression (31.2 % versus 55.6 %, p = 0.002) and time to progression (p &lt; 0.001) when patients were divided into Stages C1 and C2 (presence or absence of pelvic side wall fixation) irrespective of their TUR status. 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subjects Actuarial Analysis
Adenocarcinoma - radiotherapy
Adenocarcinoma - secondary
Adenocarcinoma - surgery
Aged
Aged, 80 and over
Combined Modality Therapy
Humans
Lymph Node Excision
Male
Middle Aged
Prognosis
Prostatectomy
Prostatic Neoplasms - radiotherapy
Prostatic Neoplasms - surgery
Radiotherapy, High-Energy
Retrospective Studies
title Dissemination of disease following transurethral resection for locally advanced prostate cancer
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