Pericardial blood activates the extrinsic coagulation pathway during clinical cardiopulmonary bypass

Coagulation during cardiopulmonary bypass (CPB) traditionally has been attributed to activation of the contact system of plasma proteins and the intrinsic coagulation pathway by blood contact with negatively charged surfaces not lined by endothelium. Recent studies have focused on the possible role...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1996-06, Vol.93 (11), p.2014-2018
Hauptverfasser:	CHUNG, J. H, GIKAKIS, N, RAO, A. K, DRAKE, T. A, COLMAN, R. W, EDMUNDS, L. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biopsy Blood Coagulation - physiology Blood Loss, Surgical - physiopathology Cardiopulmonary Bypass - adverse effects Factor VII - analysis Factor VIIa - analysis Humans Medical sciences Middle Aged Monocytes - metabolism Peptide Fragments - analysis Pericardium - injuries Pericardium - pathology Prothrombin - analysis Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Thromboplastin - analysis Thrombosis - etiology
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