Laparoscopic surgery for neuroblastoma identified by mass screening

Most neuroblastomas identified by mass screening are clearly different from the clinically diagnosed tumors with respect to biology, epidemiology, and outcome. Because the neuroblastomas detected by mass screening have favorable biological features (97% survival rate at 5 years), aggressive surgery...

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Veröffentlicht in:Journal of pediatric surgery 1996-03, Vol.31 (3), p.385-388
Hauptverfasser: Yamamoto, Hirotoshi, Yoshida, Mitsuhiro, Sera, Yoshihisa
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container_title Journal of pediatric surgery
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creator Yamamoto, Hirotoshi
Yoshida, Mitsuhiro
Sera, Yoshihisa
description Most neuroblastomas identified by mass screening are clearly different from the clinically diagnosed tumors with respect to biology, epidemiology, and outcome. Because the neuroblastomas detected by mass screening have favorable biological features (97% survival rate at 5 years), aggressive surgery may not be appropriate for such tumors. Laparoscopic adrenalectomy was performed on a 9-month-old boy and two 8-month-old girls who had suitable lesions. The tumors were small (
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Because the neuroblastomas detected by mass screening have favorable biological features (97% survival rate at 5 years), aggressive surgery may not be appropriate for such tumors. Laparoscopic adrenalectomy was performed on a 9-month-old boy and two 8-month-old girls who had suitable lesions. The tumors were small (&lt;20 mm in diameter). With the patients under general anesthesia, five trocars were placed in the abdomen. The abdominal wall traction method was used in addition to pneumoperitoneum. Intraabdominal pressure was maintained at below 4 mm Hg. The adrenal tumors were well encapsulated and completely excised, placed into a plastic bag, and removed through one of the 10-mm trocar sites. No lymphadenopathy was observed. The postoperative course was uneventful. The tumors were of favorable Shimada histology and had no N- myc gene amplification. 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Because the neuroblastomas detected by mass screening have favorable biological features (97% survival rate at 5 years), aggressive surgery may not be appropriate for such tumors. Laparoscopic adrenalectomy was performed on a 9-month-old boy and two 8-month-old girls who had suitable lesions. The tumors were small (&lt;20 mm in diameter). With the patients under general anesthesia, five trocars were placed in the abdomen. The abdominal wall traction method was used in addition to pneumoperitoneum. Intraabdominal pressure was maintained at below 4 mm Hg. The adrenal tumors were well encapsulated and completely excised, placed into a plastic bag, and removed through one of the 10-mm trocar sites. No lymphadenopathy was observed. The postoperative course was uneventful. The tumors were of favorable Shimada histology and had no N- myc gene amplification. The patients have survived, with no evidence of recurrence or metastasis, through the follow-up period of 17 to 22 months.</description><subject>Abdomen</subject><subject>Adrenal Gland Neoplasms - surgery</subject><subject>Adrenal Gland Neoplasms - urine</subject><subject>Adrenalectomy - methods</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Homovanillic Acid - urine</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Laparoscopy - methods</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neonatal Screening</subject><subject>Neuroblastoma - surgery</subject><subject>Neuroblastoma - urine</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Transplantations, organ and tissue grafts. 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Because the neuroblastomas detected by mass screening have favorable biological features (97% survival rate at 5 years), aggressive surgery may not be appropriate for such tumors. Laparoscopic adrenalectomy was performed on a 9-month-old boy and two 8-month-old girls who had suitable lesions. The tumors were small (&lt;20 mm in diameter). With the patients under general anesthesia, five trocars were placed in the abdomen. The abdominal wall traction method was used in addition to pneumoperitoneum. Intraabdominal pressure was maintained at below 4 mm Hg. The adrenal tumors were well encapsulated and completely excised, placed into a plastic bag, and removed through one of the 10-mm trocar sites. No lymphadenopathy was observed. The postoperative course was uneventful. The tumors were of favorable Shimada histology and had no N- myc gene amplification. The patients have survived, with no evidence of recurrence or metastasis, through the follow-up period of 17 to 22 months.</abstract><cop>Philadelphia, PA</cop><pub>Elsevier Inc</pub><pmid>8708908</pmid><doi>10.1016/S0022-3468(96)90743-5</doi><tpages>4</tpages></addata></record>
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subjects Abdomen
Adrenal Gland Neoplasms - surgery
Adrenal Gland Neoplasms - urine
Adrenalectomy - methods
Biological and medical sciences
Female
Follow-Up Studies
Homovanillic Acid - urine
Humans
Infant
Infant, Newborn
Laparoscopy - methods
Male
Medical sciences
Neonatal Screening
Neuroblastoma - surgery
Neuroblastoma - urine
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the digestive system
Survival Analysis
Treatment Outcome
Vanilmandelic Acid - urine
title Laparoscopic surgery for neuroblastoma identified by mass screening
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