Regulation of Cytokine Production by Sugi Allergen–Pullulan Conjugate

Sugi basic protein (SBP), a major allergen of Japanese cedar (Cryptomeria japonica) pollen, conjugated to pullulan (α-1,4′-, α-1,6′-glucan) reportedly suppresses IgE anti-SBP antibody production and enhances IgG anti-SBP antibody production in mice. We analyzed cytokine production by SBP-specific T...

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Veröffentlicht in:	Cellular immunology 1996-03, Vol.168 (2), p.211-219
Hauptverfasser:	Kohno, Keizo, Ohtsuki, Takashi, Suemoto, Yasuo, Inoue, Toshiya, Taniguchi, Yoshifumi, Usui, Mitsuko, Ikeda, Masao, Kurimoto, Masashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - pharmacology Animals Antigen-Presenting Cells - immunology Antigens, Plant Cells, Cultured Clone Cells - drug effects Clone Cells - immunology Clone Cells - metabolism Cryptomeria japonica Female Gene Expression Regulation - drug effects Glucans - pharmacology Immunologic Factors - pharmacology Interferon-gamma - biosynthesis Interferon-gamma - genetics Interleukin-1 - pharmacology Interleukins - biosynthesis Interleukins - genetics Lymphocyte Activation - drug effects Lymphokines - biosynthesis Lymphokines - genetics Mice Mice, Inbred BALB C Plant Proteins - pharmacology Pollen Recombinant Proteins - pharmacology T-Lymphocyte Subsets - drug effects T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocytes, Helper-Inducer - drug effects T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Helper-Inducer - metabolism
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