Morphine-induced conformational changes in human monocytes, granulocytes, and endothelial cells and in invertebrate immunocytes and microglia are mediated by nitric oxide

We evaluated the contribution of nitric oxide (NO) to morphine-induced rounding of spontaneously activated (mobile) ameboid human monocytes, granulocytes, or arterial endothelial cells and invertebrate immunocytes and microglia. Morphine induced significant rounding and inactivation of ameboid cells...

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Veröffentlicht in:	The Journal of immunology (1950) 1996-06, Vol.156 (12), p.4845-4850
Hauptverfasser:	Magazine, HI, Liu, Y, Bilfinger, TV, Fricchione, GL, Stefano, GB
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bivalvia Cell Size - drug effects Cells, Cultured Endothelium, Vascular - cytology Enzyme Inhibitors - pharmacology Granulocytes - cytology Humans Microglia - cytology Monocytes - cytology Morphine - pharmacology Nitric Oxide - pharmacology Nitric Oxide Synthase - antagonists & inhibitors Time Factors
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