Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes

Celiac disease is tightly linked to the MHC class II region on chromosome 6. We have studied two highly polymorphic microsatellite loci, TNFa and b, near the TNF genes in the class III region of the MHC, for evidence of their association to CD, as compared to a control population. Our findings show...

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Veröffentlicht in:	Human immunology 1996, Vol.45 (1), p.24-31
Hauptverfasser:	McManus, Ross, Moloney, Manus, Borton, Meriel, Finch, Anthony, Chuan, Yeong-T., Lawlor, Emer, Weir, Donald G., Kelleher, Dermot
Format:	Artikel
Sprache:	eng
Schlagworte:	Celiac Disease - genetics Disease Susceptibility DNA, Satellite - immunology Haplotypes Histocompatibility Testing Humans Linkage Disequilibrium Microsatellite Repeats - genetics Odds Ratio Polymorphism, Genetic - immunology Tumor Necrosis Factor-alpha - genetics
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