Effect of stobadine on Cu ++-mediated oxidation of low-density lipoprotein

The pyridoindole derivative stobadine [(−)-cis-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido(4,3b) indole] has been described as a drug with antihypoxic and antiarrhythmic cardioprotective properties. The antioxidative properties of this compound were studied during Cu ++-mediated low-density lipop...

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Veröffentlicht in:	Biochemical pharmacology 1996-05, Vol.51 (10), p.1277-1282
Hauptverfasser:	Horakova, Lubica, Gieß, auf, Andreas, Raber, Georg, Esterbauer, Hermann
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult antioxidant Antioxidants - pharmacology Biological and medical sciences Carbolines - pharmacology Copper - pharmacology Dose-Response Relationship, Drug Humans LDL Lipid Peroxidation Lipoproteins, LDL - drug effects Lipoproteins, LDL - metabolism Medical sciences Neuropharmacology Neuroprotective agent Pharmacology. Drug treatments stobadine tryptophan Tryptophan - metabolism
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