Characterization of transducin from bovine retinal rod outer segments. Use of monoclonal antibodies to probe the structure and function of the subunit

A panel of monoclonal antibodies has been developed against the T alpha, T beta and T gamma subunits of bovine transducin. Two anti-T alpha antibodies from this panel (TF15 and TF16) and a third one (4A) against frog T alpha (Witt, P. L., Hamm, H. E., and Bownds, M. D. (1984) J. Gen. Physiol. 84, 25...

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Veröffentlicht in:	The Journal of biological chemistry 1988-01, Vol.263 (1), p.489-496
Hauptverfasser:	Navon, S E, Fung, B K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Antigen-Antibody Complex Binding, Competitive Cattle GTP-Binding Proteins - metabolism Guanosine 5'-O-(3-Thiotriphosphate) Guanosine Triphosphate - analogs & derivatives Guanosine Triphosphate - metabolism Kinetics Macromolecular Substances Membrane Proteins - immunology Membrane Proteins - metabolism Photoreceptor Cells - metabolism Rod Cell Outer Segment - metabolism Thionucleotides - metabolism Transducin
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