Thin-section computed tomography scans detect medullary cysts in patients believed to have juvenile nephronophthisis
Juvenile nephronophthisis (NPH) and medullary cystic kidney disease are an important cause of chronic renal failure in children and young adults. Medullary cysts are regarded as the hallmark of this condition. The diagnostic techniques that were used previously were not conclusive in most cases to d...
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| Veröffentlicht in: | American journal of kidney diseases 1996-02, Vol.27 (2), p.216-219 |
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| container_title | American journal of kidney diseases |
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| creator | Elzouki, Abdelaziz Y. Al-Suhaibani, Hamad Mirza, Khalid Al-Sowailem, Abdul Mohsen |
| description | Juvenile nephronophthisis (NPH) and medullary cystic kidney disease are an important cause of chronic renal failure in children and young adults. Medullary cysts are regarded as the hallmark of this condition. The diagnostic techniques that were used previously were not conclusive in most cases to demonstrate medullary cysts. We studied the role of thin-section (1.5-mm) computed tomography (CT) scan as an optimal imaging diagnostic technique. Three children who were admitted to our hospital consecutive with a clinical diagnosis of NPH were included. We found that the thin-section CT scan demonstrates the medullary cysts in all patients. We recommend CT scan as the investigation of choice in patients with clinical features suggestive of nephronophthisis-cystic renal medulla complex. |
| doi_str_mv | 10.1016/S0272-6386(96)90543-0 |
| format | Article |
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Medullary cysts are regarded as the hallmark of this condition. The diagnostic techniques that were used previously were not conclusive in most cases to demonstrate medullary cysts. We studied the role of thin-section (1.5-mm) computed tomography (CT) scan as an optimal imaging diagnostic technique. Three children who were admitted to our hospital consecutive with a clinical diagnosis of NPH were included. We found that the thin-section CT scan demonstrates the medullary cysts in all patients. 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Medullary cysts are regarded as the hallmark of this condition. The diagnostic techniques that were used previously were not conclusive in most cases to demonstrate medullary cysts. We studied the role of thin-section (1.5-mm) computed tomography (CT) scan as an optimal imaging diagnostic technique. Three children who were admitted to our hospital consecutive with a clinical diagnosis of NPH were included. We found that the thin-section CT scan demonstrates the medullary cysts in all patients. We recommend CT scan as the investigation of choice in patients with clinical features suggestive of nephronophthisis-cystic renal medulla complex.</description><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Consanguinity</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Kidney Diseases, Cystic - complications</subject><subject>Kidney Diseases, Cystic - diagnostic imaging</subject><subject>Kidney Diseases, Cystic - genetics</subject><subject>Kidney Failure, Chronic - etiology</subject><subject>Kidney Medulla - diagnostic imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Radiodiagnosis. Nmr imagery. 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Nmr imagery. Nmr spectrometry</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Urinary system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elzouki, Abdelaziz Y.</creatorcontrib><creatorcontrib>Al-Suhaibani, Hamad</creatorcontrib><creatorcontrib>Mirza, Khalid</creatorcontrib><creatorcontrib>Al-Sowailem, Abdul Mohsen</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of kidney diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elzouki, Abdelaziz Y.</au><au>Al-Suhaibani, Hamad</au><au>Mirza, Khalid</au><au>Al-Sowailem, Abdul Mohsen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thin-section computed tomography scans detect medullary cysts in patients believed to have juvenile nephronophthisis</atitle><jtitle>American journal of kidney diseases</jtitle><addtitle>Am J Kidney Dis</addtitle><date>1996-02-01</date><risdate>1996</risdate><volume>27</volume><issue>2</issue><spage>216</spage><epage>219</epage><pages>216-219</pages><issn>0272-6386</issn><eissn>1523-6838</eissn><abstract>Juvenile nephronophthisis (NPH) and medullary cystic kidney disease are an important cause of chronic renal failure in children and young adults. Medullary cysts are regarded as the hallmark of this condition. The diagnostic techniques that were used previously were not conclusive in most cases to demonstrate medullary cysts. We studied the role of thin-section (1.5-mm) computed tomography (CT) scan as an optimal imaging diagnostic technique. Three children who were admitted to our hospital consecutive with a clinical diagnosis of NPH were included. We found that the thin-section CT scan demonstrates the medullary cysts in all patients. We recommend CT scan as the investigation of choice in patients with clinical features suggestive of nephronophthisis-cystic renal medulla complex.</abstract><cop>Orlando, FL</cop><pub>Elsevier Inc</pub><pmid>8659496</pmid><doi>10.1016/S0272-6386(96)90543-0</doi><tpages>4</tpages></addata></record> |
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| ispartof | American journal of kidney diseases, 1996-02, Vol.27 (2), p.216-219 |
| issn | 0272-6386 1523-6838 |
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| subjects | Biological and medical sciences Child Consanguinity Female Humans Investigative techniques, diagnostic techniques (general aspects) Kidney Diseases, Cystic - complications Kidney Diseases, Cystic - diagnostic imaging Kidney Diseases, Cystic - genetics Kidney Failure, Chronic - etiology Kidney Medulla - diagnostic imaging Male Medical sciences Radiodiagnosis. Nmr imagery. Nmr spectrometry Tomography, X-Ray Computed - methods Urinary system |
| title | Thin-section computed tomography scans detect medullary cysts in patients believed to have juvenile nephronophthisis |
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