Insulin receptor mediates inhibitory effect of insulin, but not of insulin-like growth factor (IGF)-I, on IGF binding protein 1 (IGFBP-1) production in human granulosa cells

Insulin-like growth factor binding proteins (IGFBPs) may participate in regulating ovarian function by modifying effects of insulin-like growth factors (IGFs) or by directly affecting ovarian steroidogenesis in both normal and pathological circumstances. The latter include hyperinsulinemic insulin r...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 1996-02, Vol.81 (2), p.493-496
Hauptverfasser:	PORETSKY, L, CHANDRASEKHER, Y. A, BAI, C, LIU, H. C, ROSENWAKS, Z, GIUDICE, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - pharmacology Biological and medical sciences Cells, Cultured Female Functional investigation of endocrine glands and genital system Granulosa Cells - drug effects Granulosa Cells - metabolism Humans Insulin - pharmacology Insulin-Like Growth Factor Binding Protein 1 - biosynthesis Insulin-Like Growth Factor I - pharmacology Investigative techniques, diagnostic techniques (general aspects) Medical sciences Progesterone - metabolism Receptor, Insulin - antagonists & inhibitors Receptor, Insulin - physiology
Online-Zugang:	Volltext
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