5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors
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| Veröffentlicht in: | Journal of medicinal chemistry 1996-05, Vol.39 (10), p.1943-1945 |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| container_end_page | 1945 |
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| container_issue | 10 |
| container_start_page | 1943 |
| container_title | Journal of medicinal chemistry |
| container_volume | 39 |
| creator | Rowley, Michael Broughton, Howard B Collins, Ian Baker, Raymond Emms, Frances Marwood, Rosemarie Patel, Shil Patel, Smita Ragan, C. Ian Freedman, Stephen B Leeson, Paul D |
| description | |
| doi_str_mv | 10.1021/jm960072u |
| format | Article |
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Ian</creatorcontrib><creatorcontrib>Freedman, Stephen B</creatorcontrib><creatorcontrib>Leeson, Paul D</creatorcontrib><title>5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors</title><title>Journal of medicinal chemistry</title><addtitle>J. Med. Chem</addtitle><subject>Biological and medical sciences</subject><subject>Catecholaminergic system</subject><subject>Cloning, Molecular</subject><subject>Dopamine Antagonists - chemistry</subject><subject>Dopamine Antagonists - pharmacology</subject><subject>Dopamine D2 Receptor Antagonists</subject><subject>Humans</subject><subject>Isoxazoles - chemistry</subject><subject>Isoxazoles - pharmacology</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>Neurotransmitters. Neurotransmission. Receptors</subject><subject>Pharmacology. 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| fulltext | fulltext |
| identifier | ISSN: 0022-2623 |
| ispartof | Journal of medicinal chemistry, 1996-05, Vol.39 (10), p.1943-1945 |
| issn | 0022-2623 1520-4804 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78042344 |
| source | ACS_美国化学学会期刊（与NSTL共建）; MEDLINE |
| subjects | Biological and medical sciences Catecholaminergic system Cloning, Molecular Dopamine Antagonists - chemistry Dopamine Antagonists - pharmacology Dopamine D2 Receptor Antagonists Humans Isoxazoles - chemistry Isoxazoles - pharmacology Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Piperidines - chemistry Piperidines - pharmacology Receptors, Dopamine D2 - genetics Receptors, Dopamine D4 |
| title | 5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors |
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