Impaired motor skill learning in schizophrenia: implications for corticostriatal dysfunction
We assessed skill learning in young and older schizophrenic patients using the rotary pursuit task. Schizophrenic patients displayed impaired learning on this task compared with normal control subjects, but older patients were not more impaired than young ones. The patients' rotary pursuit lear...
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| Veröffentlicht in: | Biological psychiatry (1969) 1996-02, Vol.39 (4), p.241-248 |
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| container_title | Biological psychiatry (1969) |
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| creator | Schwartz, Barbara L. Rosse, Richard B. Veazey, Catherine Deutsch, Stephen I. |
| description | We assessed skill learning in young and older schizophrenic patients using the rotary pursuit task. Schizophrenic patients displayed impaired learning on this task compared with normal control subjects, but older patients were not more impaired than young ones. The patients' rotary pursuit learning was not correlated to the severity of abnormal movements or to their treatment with medication, but it was associated to conceptual abilities assessed on the Dementia Rating Scale (
Mattis 1988). An impairment in acquiring motor procedures in this task might reflect neuropsychological deficits associated with corticostriatal pathology. |
| doi_str_mv | 10.1016/0006-3223(95)00130-1 |
| format | Article |
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Mattis 1988). An impairment in acquiring motor procedures in this task might reflect neuropsychological deficits associated with corticostriatal pathology.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cerebral Cortex - physiopathology</subject><subject>Corpus Striatum - physiopathology</subject><subject>dementia</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>memory</subject><subject>Mental Recall - physiology</subject><subject>Middle Aged</subject><subject>motor skills</subject><subject>Motor Skills - physiology</subject><subject>Neuropsychological Tests</subject><subject>Problem Solving - physiology</subject><subject>procedural learning</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychomotor Disorders - diagnosis</subject><subject>Psychomotor Disorders - physiopathology</subject><subject>Psychomotor Disorders - psychology</subject><subject>Psychomotor Performance - physiology</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychoses</subject><subject>Pursuit, Smooth - physiology</subject><subject>Schizophrenia</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - physiopathology</subject><subject>Schizophrenic Psychology</subject><issn>0006-3223</issn><issn>1873-2402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1r3DAQhkVpSTdJ_0EKPpSQHtzoy5KcQ6CEfgQCvaS3gtCO5WZaWXIlbyH59dVmlz32okHM8w7DM4ScMfqBUaYuKaWqFZyLi757TykTtGUvyIoZLVouKX9JVgfkNTku5Vf9as7ZETkySnZa0xX5cTvNDrMfmiktKTflN4bQBO9yxPizwdgUeMCnND9kH9FdNTjNAcEtmGJpxpqAlBeEVJaMbnGhGR7LuImwBU7Jq9GF4t_s6wn5_vnT_c3X9u7bl9ubj3ctyN4sreyFHuigFTgHSg4gvJHgux4U8J5pZUZj1pxrDsYBKKaYdOCEF7D29RUn5Hw3d87pz8aXxU5YwIfgok-bYrWhktGuq6DcgZBTKdmPds44ufxoGbVbqXZrzG6N2b6zz1Itq7G3-_mb9eSHQ2hvsfbf7fuugAtjdhGwHDDe91oJU7HrHeari7_osy2APoIf6gFgsUPC_-_xD1r0lLg</recordid><startdate>19960215</startdate><enddate>19960215</enddate><creator>Schwartz, Barbara L.</creator><creator>Rosse, Richard B.</creator><creator>Veazey, Catherine</creator><creator>Deutsch, Stephen I.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19960215</creationdate><title>Impaired motor skill learning in schizophrenia: implications for corticostriatal dysfunction</title><author>Schwartz, Barbara L. ; Rosse, Richard B. ; Veazey, Catherine ; Deutsch, Stephen I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-4937d0d76caac64dc3e84ce59c6c291768f88b2272c8acc61614aca3e3cbe3e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cerebral Cortex - physiopathology</topic><topic>Corpus Striatum - physiopathology</topic><topic>dementia</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>memory</topic><topic>Mental Recall - physiology</topic><topic>Middle Aged</topic><topic>motor skills</topic><topic>Motor Skills - physiology</topic><topic>Neuropsychological Tests</topic><topic>Problem Solving - physiology</topic><topic>procedural learning</topic><topic>Psychology. 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Psychiatry</topic><topic>Psychoses</topic><topic>Pursuit, Smooth - physiology</topic><topic>Schizophrenia</topic><topic>Schizophrenia - diagnosis</topic><topic>Schizophrenia - physiopathology</topic><topic>Schizophrenic Psychology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schwartz, Barbara L.</creatorcontrib><creatorcontrib>Rosse, Richard B.</creatorcontrib><creatorcontrib>Veazey, Catherine</creatorcontrib><creatorcontrib>Deutsch, Stephen I.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biological psychiatry (1969)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schwartz, Barbara L.</au><au>Rosse, Richard B.</au><au>Veazey, Catherine</au><au>Deutsch, Stephen I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impaired motor skill learning in schizophrenia: implications for corticostriatal dysfunction</atitle><jtitle>Biological psychiatry (1969)</jtitle><addtitle>Biol Psychiatry</addtitle><date>1996-02-15</date><risdate>1996</risdate><volume>39</volume><issue>4</issue><spage>241</spage><epage>248</epage><pages>241-248</pages><issn>0006-3223</issn><eissn>1873-2402</eissn><coden>BIPCBF</coden><abstract>We assessed skill learning in young and older schizophrenic patients using the rotary pursuit task. Schizophrenic patients displayed impaired learning on this task compared with normal control subjects, but older patients were not more impaired than young ones. The patients' rotary pursuit learning was not correlated to the severity of abnormal movements or to their treatment with medication, but it was associated to conceptual abilities assessed on the Dementia Rating Scale (
Mattis 1988). An impairment in acquiring motor procedures in this task might reflect neuropsychological deficits associated with corticostriatal pathology.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>8645770</pmid><doi>10.1016/0006-3223(95)00130-1</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adult Adult and adolescent clinical studies Age Factors Aged Biological and medical sciences Cerebral Cortex - physiopathology Corpus Striatum - physiopathology dementia Female Humans Male Medical sciences memory Mental Recall - physiology Middle Aged motor skills Motor Skills - physiology Neuropsychological Tests Problem Solving - physiology procedural learning Psychology. Psychoanalysis. Psychiatry Psychomotor Disorders - diagnosis Psychomotor Disorders - physiopathology Psychomotor Disorders - psychology Psychomotor Performance - physiology Psychopathology. Psychiatry Psychoses Pursuit, Smooth - physiology Schizophrenia Schizophrenia - diagnosis Schizophrenia - physiopathology Schizophrenic Psychology |
| title | Impaired motor skill learning in schizophrenia: implications for corticostriatal dysfunction |
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