The influence of buffer species and strength on diltiazem HCl release from beads coated with the aqueous cationic polymer dispersions, eudragit RS, RL 30D

Eudragit RL and RS 30D are pseudolatexes frequently used in the coating of solid dosage forms. They are based on cationic copolymers stabilized with quaternary ammonium groups (poly(ethylacrylate-methylmethacrylate-trimethylammonioethyl methacrylate chloride). A pH-independent drug release is expect...

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Veröffentlicht in:	Pharmaceutical research 1996, Vol.13 (1), p.52-56
Hauptverfasser:	BODMEIER, R, XIAODI GUO, SARABIA, R. E, SKULTETY, P. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins Biological and medical sciences Buffers Cations Diltiazem - metabolism General pharmacology Hydrogen-Ion Concentration Medical sciences Microspheres Osmolar Concentration Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymers Water - chemistry
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