Ultrafast Glycerophospholipid-selective Transbilayer Motion Mediated by a Protein in the Endoplasmic Reticulum Membrane

A relatively rapid transbilayer motion of phospholipids in the microsomal membrane seems to be required due to their asymmetric synthesis in the cytoplasmic leaflet. Marked discrepancies exist with regard to the rate and specificity of this flip-flop process. To reinvestigate this problem, we have u...

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Veröffentlicht in:	The Journal of biological chemistry 1996-03, Vol.271 (12), p.6651-6657
Hauptverfasser:	Buton, X, Morrot, G, Fellmann, P, Seigneuret, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Endoplasmic Reticulum, Rough - metabolism Lipid Bilayers Magnetic Resonance Spectroscopy Male Membrane Proteins - metabolism Phosphatidic Acids - metabolism Phosphorus Isotopes Rats Rats, Wistar
Online-Zugang:	Volltext
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