isolation and characterisation of the ovine growth hormone gene
The ovine growth hormone gene has been isolated and sequenced, together with about 1 kbp of DNA flanking each end of the gene. The structure of the gene is similar to that found for other growth hormone genes, particularly the bovine gene, and has a primary transcript of 1792 bp, with five exons, an...
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Veröffentlicht in: | Australian journal of biological sciences 1987, Vol.40 (4), p.459-468 |
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creator | Byrne, C.R Wilson, B.W Ward, K.A |
description | The ovine growth hormone gene has been isolated and sequenced, together with about 1 kbp of DNA flanking each end of the gene. The structure of the gene is similar to that found for other growth hormone genes, particularly the bovine gene, and has a primary transcript of 1792 bp, with five exons, and with intron sizes of 264 bp, 231 bp, 227 bp and 273 bp. The gene is flanked by artiodactyl-specific middle-repetitive DNA, consisting mainly of elements belonging to the 'C-A3' family of repeated DNA. A previously unreported sequence has been found, which we have named an 'E' element. |
doi_str_mv | 10.1071/BI9870459 |
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The structure of the gene is similar to that found for other growth hormone genes, particularly the bovine gene, and has a primary transcript of 1792 bp, with five exons, and with intron sizes of 264 bp, 231 bp, 227 bp and 273 bp. The gene is flanked by artiodactyl-specific middle-repetitive DNA, consisting mainly of elements belonging to the 'C-A3' family of repeated DNA. A previously unreported sequence has been found, which we have named an 'E' element.</description><identifier>ISSN: 0004-9417</identifier><identifier>DOI: 10.1071/BI9870459</identifier><identifier>PMID: 3453044</identifier><language>eng</language><publisher>Australia</publisher><subject>Amino Acid Sequence ; Animals ; Base Sequence ; characterization ; Chromosome Mapping ; DNA - genetics ; Exons ; genes ; Growth Hormone - genetics ; growth promotion ; hormones ; Introns ; isolation ; Molecular Sequence Data ; Nucleic Acid Hybridization ; Repetitive Sequences, Nucleic Acid ; sheep ; Sheep - genetics ; somatotropin ; ultrastructure</subject><ispartof>Australian journal of biological sciences, 1987, Vol.40 (4), p.459-468</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-3f566417dcda4ed10883942cdc6d9281b72fa57a5ad90579119844b7cbb711763</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,3352,4026,27930,27931,27932</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3453044$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Byrne, C.R</creatorcontrib><creatorcontrib>Wilson, B.W</creatorcontrib><creatorcontrib>Ward, K.A</creatorcontrib><title>isolation and characterisation of the ovine growth hormone gene</title><title>Australian journal of biological sciences</title><addtitle>Aust J Biol Sci</addtitle><description>The ovine growth hormone gene has been isolated and sequenced, together with about 1 kbp of DNA flanking each end of the gene. The structure of the gene is similar to that found for other growth hormone genes, particularly the bovine gene, and has a primary transcript of 1792 bp, with five exons, and with intron sizes of 264 bp, 231 bp, 227 bp and 273 bp. The gene is flanked by artiodactyl-specific middle-repetitive DNA, consisting mainly of elements belonging to the 'C-A3' family of repeated DNA. A previously unreported sequence has been found, which we have named an 'E' element.</description><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Base Sequence</subject><subject>characterization</subject><subject>Chromosome Mapping</subject><subject>DNA - genetics</subject><subject>Exons</subject><subject>genes</subject><subject>Growth Hormone - genetics</subject><subject>growth promotion</subject><subject>hormones</subject><subject>Introns</subject><subject>isolation</subject><subject>Molecular Sequence Data</subject><subject>Nucleic Acid Hybridization</subject><subject>Repetitive Sequences, Nucleic Acid</subject><subject>sheep</subject><subject>Sheep - genetics</subject><subject>somatotropin</subject><subject>ultrastructure</subject><issn>0004-9417</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMtOwzAQRb0AlVJY8AGIrJBYBMavOF4hWvGoVIkFdG05ttMEJXGxUxB_T6pUXY1m7tHV6CB0heEeg8AP86XMBTAuT9AUAFgqGRZn6DzGLwAKRIoJmlDGKTA2RY919I3ua98lurOJqXTQpnehjuPRl0lfucT_1J1LNsH_9lVS-dD6_eo6d4FOS91Ed3mYM7R-ef5cvKWr99fl4mmVGkpln9KSZ9nwhzVWM2cx5DmVjBhrMitJjgtBSs2F5tpK4EJiLHPGCmGKQmAsMjpDt2PvNvjvnYu9autoXNPozvldVCIHSqhgA3g3gib4GIMr1TbUrQ5_CoPaC1JHQQN7fSjdFa2zR_JgZ8hvxrzUXunNIEWtPwhgCpiBIJzQf_ydajY</recordid><startdate>1987</startdate><enddate>1987</enddate><creator>Byrne, C.R</creator><creator>Wilson, B.W</creator><creator>Ward, K.A</creator><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1987</creationdate><title>isolation and characterisation of the ovine growth hormone gene</title><author>Byrne, C.R ; Wilson, B.W ; Ward, K.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-3f566417dcda4ed10883942cdc6d9281b72fa57a5ad90579119844b7cbb711763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Base Sequence</topic><topic>characterization</topic><topic>Chromosome Mapping</topic><topic>DNA - genetics</topic><topic>Exons</topic><topic>genes</topic><topic>Growth Hormone - genetics</topic><topic>growth promotion</topic><topic>hormones</topic><topic>Introns</topic><topic>isolation</topic><topic>Molecular Sequence Data</topic><topic>Nucleic Acid Hybridization</topic><topic>Repetitive Sequences, Nucleic Acid</topic><topic>sheep</topic><topic>Sheep - genetics</topic><topic>somatotropin</topic><topic>ultrastructure</topic><toplevel>online_resources</toplevel><creatorcontrib>Byrne, C.R</creatorcontrib><creatorcontrib>Wilson, B.W</creatorcontrib><creatorcontrib>Ward, K.A</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Australian journal of biological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Byrne, C.R</au><au>Wilson, B.W</au><au>Ward, K.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>isolation and characterisation of the ovine growth hormone gene</atitle><jtitle>Australian journal of biological sciences</jtitle><addtitle>Aust J Biol Sci</addtitle><date>1987</date><risdate>1987</risdate><volume>40</volume><issue>4</issue><spage>459</spage><epage>468</epage><pages>459-468</pages><issn>0004-9417</issn><abstract>The ovine growth hormone gene has been isolated and sequenced, together with about 1 kbp of DNA flanking each end of the gene. The structure of the gene is similar to that found for other growth hormone genes, particularly the bovine gene, and has a primary transcript of 1792 bp, with five exons, and with intron sizes of 264 bp, 231 bp, 227 bp and 273 bp. The gene is flanked by artiodactyl-specific middle-repetitive DNA, consisting mainly of elements belonging to the 'C-A3' family of repeated DNA. A previously unreported sequence has been found, which we have named an 'E' element.</abstract><cop>Australia</cop><pmid>3453044</pmid><doi>10.1071/BI9870459</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; CSIRO Publishing Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Amino Acid Sequence Animals Base Sequence characterization Chromosome Mapping DNA - genetics Exons genes Growth Hormone - genetics growth promotion hormones Introns isolation Molecular Sequence Data Nucleic Acid Hybridization Repetitive Sequences, Nucleic Acid sheep Sheep - genetics somatotropin ultrastructure |
title | isolation and characterisation of the ovine growth hormone gene |
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