isolation and characterisation of the ovine growth hormone gene

The ovine growth hormone gene has been isolated and sequenced, together with about 1 kbp of DNA flanking each end of the gene. The structure of the gene is similar to that found for other growth hormone genes, particularly the bovine gene, and has a primary transcript of 1792 bp, with five exons, an...

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Veröffentlicht in:Australian journal of biological sciences 1987, Vol.40 (4), p.459-468
Hauptverfasser: Byrne, C.R, Wilson, B.W, Ward, K.A
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container_title Australian journal of biological sciences
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Wilson, B.W
Ward, K.A
description The ovine growth hormone gene has been isolated and sequenced, together with about 1 kbp of DNA flanking each end of the gene. The structure of the gene is similar to that found for other growth hormone genes, particularly the bovine gene, and has a primary transcript of 1792 bp, with five exons, and with intron sizes of 264 bp, 231 bp, 227 bp and 273 bp. The gene is flanked by artiodactyl-specific middle-repetitive DNA, consisting mainly of elements belonging to the 'C-A3' family of repeated DNA. A previously unreported sequence has been found, which we have named an 'E' element.
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subjects Amino Acid Sequence
Animals
Base Sequence
characterization
Chromosome Mapping
DNA - genetics
Exons
genes
Growth Hormone - genetics
growth promotion
hormones
Introns
isolation
Molecular Sequence Data
Nucleic Acid Hybridization
Repetitive Sequences, Nucleic Acid
sheep
Sheep - genetics
somatotropin
ultrastructure
title isolation and characterisation of the ovine growth hormone gene
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