Wessely-type immune ring following phototherapeutic keratectomy
Immune rings following photorefractive keratectomy (PRK) have been reported but have not been described in detail. This case report describes an immune ring after phototherapeutic keratectomy (PTK) in a patient with long-standing superficial corneal scars. A dense white ring formed in the peripheral...
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Veröffentlicht in: | Journal of cataract and refractive surgery 1996-01, Vol.22 (1), p.142-146 |
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description | Immune rings following photorefractive keratectomy (PRK) have been reported but have not been described in detail. This case report describes an immune ring after phototherapeutic keratectomy (PTK) in a patient with long-standing superficial corneal scars. A dense white ring formed in the peripheral cornea on the fourth day following surgery. The patient was treated with antibiotics until negative cultures were reported 48 hours later. A biopsy was taken and examined by light microscopy using hematoxylin-eosin and Mason's trichrome staining. The stroma showed focal keratocyte depopulation with nuclear fragments, occasional polymorphonuclear leucocytes, and an active fibroblastic reaction. No lymphocytes or plasma cells were seen. Clinically, the immune ring faded slowly and was still apparent 9 months after the PTK. Studies of similar cases are required to clarify the mechanisms responsible for this phenomenon. |
doi_str_mv | 10.1016/S0886-3350(96)80284-7 |
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This case report describes an immune ring after phototherapeutic keratectomy (PTK) in a patient with long-standing superficial corneal scars. A dense white ring formed in the peripheral cornea on the fourth day following surgery. The patient was treated with antibiotics until negative cultures were reported 48 hours later. A biopsy was taken and examined by light microscopy using hematoxylin-eosin and Mason's trichrome staining. The stroma showed focal keratocyte depopulation with nuclear fragments, occasional polymorphonuclear leucocytes, and an active fibroblastic reaction. No lymphocytes or plasma cells were seen. Clinically, the immune ring faded slowly and was still apparent 9 months after the PTK. Studies of similar cases are required to clarify the mechanisms responsible for this phenomenon.</description><identifier>ISSN: 0886-3350</identifier><identifier>EISSN: 1873-4502</identifier><identifier>DOI: 10.1016/S0886-3350(96)80284-7</identifier><identifier>PMID: 8656353</identifier><identifier>CODEN: JCSUEV</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Arthus Reaction - immunology ; Biological and medical sciences ; Cataract Extraction ; Cornea - immunology ; Cornea - pathology ; Corneal Opacity - immunology ; Corneal Opacity - pathology ; Corneal Stroma - immunology ; Corneal Stroma - pathology ; Humans ; Keratoplasty, Penetrating ; Lasers, Excimer ; Male ; Medical sciences ; Photorefractive Keratectomy ; Postoperative Complications - immunology ; Postoperative Complications - pathology ; Reoperation ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the eye and orbit ; Wound Healing - physiology</subject><ispartof>Journal of cataract and refractive surgery, 1996-01, Vol.22 (1), p.142-146</ispartof><rights>1996 American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-c0a1041d07729963bf1a2a138dd730be09d1d33bf10ff1ef03ff52c39ebc7e93</citedby><cites>FETCH-LOGICAL-c389t-c0a1041d07729963bf1a2a138dd730be09d1d33bf10ff1ef03ff52c39ebc7e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0886-3350(96)80284-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995,58550</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2986017$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8656353$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Teichmann, Klaus D.</creatorcontrib><creatorcontrib>Cameron, James</creatorcontrib><creatorcontrib>Huaman, Antonio</creatorcontrib><creatorcontrib>Rahi, Amjad H.S.</creatorcontrib><creatorcontrib>Badr, Ihsan</creatorcontrib><title>Wessely-type immune ring following phototherapeutic keratectomy</title><title>Journal of cataract and refractive surgery</title><addtitle>J Cataract Refract Surg</addtitle><description>Immune rings following photorefractive keratectomy (PRK) have been reported but have not been described in detail. This case report describes an immune ring after phototherapeutic keratectomy (PTK) in a patient with long-standing superficial corneal scars. A dense white ring formed in the peripheral cornea on the fourth day following surgery. The patient was treated with antibiotics until negative cultures were reported 48 hours later. A biopsy was taken and examined by light microscopy using hematoxylin-eosin and Mason's trichrome staining. The stroma showed focal keratocyte depopulation with nuclear fragments, occasional polymorphonuclear leucocytes, and an active fibroblastic reaction. No lymphocytes or plasma cells were seen. Clinically, the immune ring faded slowly and was still apparent 9 months after the PTK. Studies of similar cases are required to clarify the mechanisms responsible for this phenomenon.</description><subject>Adult</subject><subject>Arthus Reaction - immunology</subject><subject>Biological and medical sciences</subject><subject>Cataract Extraction</subject><subject>Cornea - immunology</subject><subject>Cornea - pathology</subject><subject>Corneal Opacity - immunology</subject><subject>Corneal Opacity - pathology</subject><subject>Corneal Stroma - immunology</subject><subject>Corneal Stroma - pathology</subject><subject>Humans</subject><subject>Keratoplasty, Penetrating</subject><subject>Lasers, Excimer</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Photorefractive Keratectomy</subject><subject>Postoperative Complications - immunology</subject><subject>Postoperative Complications - pathology</subject><subject>Reoperation</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the eye and orbit</subject><subject>Wound Healing - physiology</subject><issn>0886-3350</issn><issn>1873-4502</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkN9LwzAQx4Moc07_hMEeRPShemnWNnkaMvwFAx8c-Biy9OKibVOTVtl_b7uNvfp0x93nvgkfQsYUbinQ9O4NOE8jxhK4FukNh5hPo-yIDCnPWDRNID4mwwNySs5C-ASAacySARnwNElZwoZk9o4hYLGJmk2NE1uWbYUTb6uPiXFF4X77rl67xjVr9KrGtrF68tW1DerGlZtzcmJUEfBiX0dk-fiwnD9Hi9enl_n9ItKMiybSoChMaQ5ZFguRspWhKlaU8TzPGKwQRE5z1o_BGIoGmDFJrJnAlc5QsBG52sXW3n23GBpZ2qCxKFSFrg0y48Bol9yByQ7U3oXg0cja21L5jaQge29y6032UqRI5dabzLq78f6BdlVifrjai-r2l_u9CloVxqtK23DAYsFToH3MbIdh5-LHopdBW6w05tZ3wmTu7D8f-QN81IrH</recordid><startdate>199601</startdate><enddate>199601</enddate><creator>Teichmann, Klaus D.</creator><creator>Cameron, James</creator><creator>Huaman, Antonio</creator><creator>Rahi, Amjad H.S.</creator><creator>Badr, Ihsan</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199601</creationdate><title>Wessely-type immune ring following phototherapeutic keratectomy</title><author>Teichmann, Klaus D. ; Cameron, James ; Huaman, Antonio ; Rahi, Amjad H.S. ; Badr, Ihsan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-c0a1041d07729963bf1a2a138dd730be09d1d33bf10ff1ef03ff52c39ebc7e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Arthus Reaction - immunology</topic><topic>Biological and medical sciences</topic><topic>Cataract Extraction</topic><topic>Cornea - immunology</topic><topic>Cornea - pathology</topic><topic>Corneal Opacity - immunology</topic><topic>Corneal Opacity - pathology</topic><topic>Corneal Stroma - immunology</topic><topic>Corneal Stroma - pathology</topic><topic>Humans</topic><topic>Keratoplasty, Penetrating</topic><topic>Lasers, Excimer</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Photorefractive Keratectomy</topic><topic>Postoperative Complications - immunology</topic><topic>Postoperative Complications - pathology</topic><topic>Reoperation</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the eye and orbit</topic><topic>Wound Healing - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Teichmann, Klaus D.</creatorcontrib><creatorcontrib>Cameron, James</creatorcontrib><creatorcontrib>Huaman, Antonio</creatorcontrib><creatorcontrib>Rahi, Amjad H.S.</creatorcontrib><creatorcontrib>Badr, Ihsan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cataract and refractive surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Teichmann, Klaus D.</au><au>Cameron, James</au><au>Huaman, Antonio</au><au>Rahi, Amjad H.S.</au><au>Badr, Ihsan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wessely-type immune ring following phototherapeutic keratectomy</atitle><jtitle>Journal of cataract and refractive surgery</jtitle><addtitle>J Cataract Refract Surg</addtitle><date>1996-01</date><risdate>1996</risdate><volume>22</volume><issue>1</issue><spage>142</spage><epage>146</epage><pages>142-146</pages><issn>0886-3350</issn><eissn>1873-4502</eissn><coden>JCSUEV</coden><abstract>Immune rings following photorefractive keratectomy (PRK) have been reported but have not been described in detail. This case report describes an immune ring after phototherapeutic keratectomy (PTK) in a patient with long-standing superficial corneal scars. A dense white ring formed in the peripheral cornea on the fourth day following surgery. The patient was treated with antibiotics until negative cultures were reported 48 hours later. A biopsy was taken and examined by light microscopy using hematoxylin-eosin and Mason's trichrome staining. The stroma showed focal keratocyte depopulation with nuclear fragments, occasional polymorphonuclear leucocytes, and an active fibroblastic reaction. No lymphocytes or plasma cells were seen. Clinically, the immune ring faded slowly and was still apparent 9 months after the PTK. Studies of similar cases are required to clarify the mechanisms responsible for this phenomenon.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>8656353</pmid><doi>10.1016/S0886-3350(96)80284-7</doi><tpages>5</tpages></addata></record> |
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subjects | Adult Arthus Reaction - immunology Biological and medical sciences Cataract Extraction Cornea - immunology Cornea - pathology Corneal Opacity - immunology Corneal Opacity - pathology Corneal Stroma - immunology Corneal Stroma - pathology Humans Keratoplasty, Penetrating Lasers, Excimer Male Medical sciences Photorefractive Keratectomy Postoperative Complications - immunology Postoperative Complications - pathology Reoperation Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the eye and orbit Wound Healing - physiology |
title | Wessely-type immune ring following phototherapeutic keratectomy |
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