Splenic lymphocyte production of an endorphin during endotoxic shock

Endogenous opioids have been reported to elicit some of the pathophysiologic responses to endotoxic shock by binding to the δ-opiate receptor. We have previously reported the production of immunoreactive (ir)-endorphin by B lymphocytes treated with bacterial lipopolysaccharide (LPS). We postulated t...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 1987-06, Vol.1 (2), p.123-133
Hauptverfasser:	Harbour, Deborah V., Smith, Eric M., Blalock, J.Edwin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocytes - metabolism Drug Resistance Fluorescent Antibody Technique Lipopolysaccharides - administration & dosage Mice Mice, Inbred C3H Pro-Opiomelanocortin - biosynthesis Pro-Opiomelanocortin - isolation & purification Pro-Opiomelanocortin - physiology Shock, Septic - etiology Shock, Septic - metabolism Shock, Septic - physiopathology Spleen - cytology Spleen - metabolism
Online-Zugang:	Volltext
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