Pulmonary administration of vasoactive substances by perfluorochemical ventilation

Therapeutic management of respiratory distress syndrome, pneumonia, and pulmonary hypertension includes delivery of biologically active agents to the neonatal lung. However, mechanical abnormalities of the lung, intrapulmonary shunting, ventilation-perfusion mismatching, and elevated surface tension...

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Veröffentlicht in:	Pediatrics (Evanston) 1996-04, Vol.97 (4), p.449-455
Hauptverfasser:	WOLFSON, M. R, GREENSPAN, J. S, SHAFFER, T. H
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2-Dipalmitoylphosphatidylcholine - pharmacokinetics Acetylcholine - administration & dosage Acid-Base Equilibrium Administration, Inhalation Adrenergic alpha blockers Adrenergic alpha-antagonists Adrenergic alpha-Antagonists - administration & dosage Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Animals, Newborn Biological and medical sciences Blood Pressure - drug effects Children Dosage and administration Dose-Response Relationship, Drug Drug therapy Drugs Emergency and intensive respiratory care Epinephrine - administration & dosage Fluorocarbons - administration & dosage Health aspects Heart Rate - drug effects Hypertension, Pulmonary - drug therapy Hypoxia - drug therapy Injections, Intravenous Innovations Intensive care medicine Lung - blood supply Lung - metabolism Lungs Medical research Medical sciences Parasympathomimetic agents Pediatric respiratory diseases Pediatrics Perfluorocarbons Pulmonary Gas Exchange Respiration, Artificial Respiratory therapy Respiratory therapy for children Sheep Sympathomimetic agents Tolazoline - administration & dosage Vasoconstrictor Agents - administration & dosage Vasodilator Agents - administration & dosage
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