GLOBAL TESTS FOR COMBINATION DRUG STUDIES IN FACTORIAL TRIALS

To test the hypothesis that there are some studied dose combinations more effective in treating a disease than their respective component doses of two drugs, Hung, Chi and Lipicky proposed two α‐level tests for normally distributed data. This paper extends the utilities of these tests to the outcome...

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Veröffentlicht in:	Statistics in medicine 1996-02, Vol.15 (3), p.233-247
1. Verfasser:	HUNG, H. M. JAMES
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Antihypertensive Agents - therapeutic use Binomial Distribution Biological and medical sciences Blood Pressure - drug effects Computerized, statistical medical data processing and models in biomedicine Drug Therapy, Combination Factor Analysis, Statistical Humans Hypertension - drug therapy Medical sciences Medical statistics Models, Statistical Monte Carlo Method Randomized Controlled Trials as Topic - statistics & numerical data Treatment Outcome
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