Aged Murine T-lymphocytes Are More Resistant to Oxidative Damage Due to the Predominance of the Cells Possessing the Memory Phenotype

Glutathione (GSH) is the most important cytosolic antioxidant. Since GSH levels are decreased with age, we hypothesized that T-lymphocytes from old mice would be more sensitive to oxidative stress. T-lymphocytes from young and old mice were exposed to hypoxanthinelxanthine oxidase, and lymphocyte vi...

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