Specific Human Cellular Immunity to bcr-abl Oncogene–Derived Peptides

Chronic myelogenous leukemia (CML) cells are characterized by a t(9;22) translocation, which can encode one of two chimeric P210 bcr-abl fusion proteins, comprising products of either the b2a2 or the b3a2 exon junction. The junctional sequences represent potentially immunogenic tumor-specific antige...

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Veröffentlicht in:	Blood 1996-05, Vol.87 (9), p.3587-3592
Hauptverfasser:	Bocchia, Monica, Korontsvit, Tatyana, Xu, Qin, Mackinnon, Stephen, Yang, Soo Young, Sette, Alessandro, Scheinberg, David A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antigens, Neoplasm - immunology Biological and medical sciences Cell Division - immunology Hematologic and hematopoietic diseases Humans Immunity, Cellular Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphocyte Activation - immunology Medical sciences Molecular Sequence Data Oncogene Proteins - immunology Peptides - chemical synthesis Peptides - immunology Protein-Tyrosine Kinases Proto-Oncogene Proteins Proto-Oncogene Proteins c-abl - immunology Proto-Oncogene Proteins c-bcr Recombinant Fusion Proteins - immunology T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - pathology Tumor Cells, Cultured
Online-Zugang:	Volltext
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