Analysis of cellular interactions in limiting dilution cultures

Limiting dilution (LD) cultures are often used to study cellular heterogeneity in responses of murine splenocytes to specific or polyclonal activation. LD titration curves often reveal a nonlinear dependence of response on input cell dose. Although ‘zigzag’ shaped curves of this kind are often inter...

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Veröffentlicht in:Journal of immunological methods 1996-02, Vol.189 (2), p.183-196
Hauptverfasser: Dozmorov, I.M., Lutsenko, G.V., Sidorov, I.A., Miller, R.A.
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Sprache:eng
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