Concomitant Mobilization of Plasma Cells and Hematopoietic Progenitors Into Peripheral Blood of Multiple Myeloma Patients: Positive Selection and Transplantation of Enriched CD34+ Cells to Remove Circulating Tumor Cells

One advantage of the use of peripheral blood stem cells (PBSCs) over autologous bone marrow would be a reduced risk of tumor cell contamination. However, the level of neoplastic cells in the PB of multiple myeloma (MM) patients after mobilization protocols is poorly investigated. In this study, we e...

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Veröffentlicht in:	Blood 1996-02, Vol.87 (4), p.1625-1634
Hauptverfasser:	Lemoli, Roberto M., Fortuna, Alessandra, Motta, Maria Rosa, Rizzi, Simonetta, Giudice, Valeria, Nannetti, Anna, Martinelli, Giovanni, Cavo, Michele, Amabile, Marilina, Mangianti, Serena, Fogli, Miriam, Conte, Roberto, Tura, Sante
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigens, CD34 - analysis Base Sequence Biological and medical sciences Blood Component Removal Bone marrow, stem cells transplantation. Graft versus host reaction Cell Separation Cytoplasm - immunology DNA Primers - chemistry Female Gamma Rays Granulocyte Colony-Stimulating Factor - therapeutic use Hematopoiesis Hematopoietic Stem Cell Transplantation - methods Hematopoietic Stem Cells - cytology Humans Immunoglobulins - metabolism Immunophenotyping Male Medical sciences Middle Aged Molecular Sequence Data Multiple Myeloma - therapy Plasma Cells - cytology Transfusions. Complications. Transfusion reactions. Cell and gene therapy Whole-Body Irradiation
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