Optimal control of interferon-γ and tumor necrosis factor-α by interleukin-10 produced in response to one HLA-DR mismatch during the primary mixed lymphocyte reaction
Interleukin (IL)-10 is an immunosuppressive cytokine potentially involved in the control of the allogeneic response. Several studies failed to detect it in mixed lymphocyte reaction supernatants. However, experiments using IL-10-specific antibodies, revealing its inhibitory action on interferon (IFN...
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Veröffentlicht in: | Transplantation 1996-02, Vol.61 (3), p.497-502 |
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