IgE in atopic dermatitis: a study of the intercellular fluid
In 33 adult patients with atopic dermatitis of mild to severe degree the concentration of IgE in serum (S) and intercellular fluid (IF) was studied by suction blister technique. The median value of IF/S-IgE was 0.20 and not different from the ratio 0.21 found in controls. Furthermore, by subdividing...
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| Veröffentlicht in: | Acta dermato-venereologica 1987-01, Vol.67 (6), p.476-480 |
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| container_end_page | 480 |
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| container_issue | 6 |
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| container_title | Acta dermato-venereologica |
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| creator | BECK, H.-I HAGDRUP, H. K BRANDRUP, F BONNEVIE-NIELSEN, V |
| description | In 33 adult patients with atopic dermatitis of mild to severe degree the concentration of IgE in serum (S) and intercellular fluid (IF) was studied by suction blister technique. The median value of IF/S-IgE was 0.20 and not different from the ratio 0.21 found in controls. Furthermore, by subdividing the patients into groups with asthma/rhinitis or different severities of eczema no significant differences in the IF/S-IgE ratios were found compared with the controls. In the controls the IF/S-IgE ratio (0.21) was significantly different from the IF/S-IgG ratio (0.32). The median ratio of IF/S-IgE divided by IF/S-IgG was 0.63, which might indicate a reduced passage of IgE into IF compared with IgG presumably dependent on differences in the molecular size or tertiary structure of the proteins. |
| doi_str_mv | 10.2340/0001555567476480 |
| format | Article |
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The median ratio of IF/S-IgE divided by IF/S-IgG was 0.63, which might indicate a reduced passage of IgE into IF compared with IgG presumably dependent on differences in the molecular size or tertiary structure of the proteins.</description><identifier>ISSN: 0001-5555</identifier><identifier>EISSN: 1651-2057</identifier><identifier>DOI: 10.2340/0001555567476480</identifier><identifier>PMID: 2451371</identifier><identifier>CODEN: ADVEA4</identifier><language>eng</language><publisher>Uppsala: Acta dermato-venereologica</publisher><subject>Adolescent ; Adult ; Aged ; Allergic diseases ; Biological and medical sciences ; Dermatitis, Atopic - immunology ; Extracellular Space - analysis ; Extracellular Space - immunology ; Female ; Humans ; Immunoglobulin E - analysis ; Immunopathology ; Male ; Medical sciences ; Middle Aged ; Skin allergic diseases. 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K</creatorcontrib><creatorcontrib>BRANDRUP, F</creatorcontrib><creatorcontrib>BONNEVIE-NIELSEN, V</creatorcontrib><title>IgE in atopic dermatitis: a study of the intercellular fluid</title><title>Acta dermato-venereologica</title><addtitle>Acta Derm Venereol</addtitle><description>In 33 adult patients with atopic dermatitis of mild to severe degree the concentration of IgE in serum (S) and intercellular fluid (IF) was studied by suction blister technique. The median value of IF/S-IgE was 0.20 and not different from the ratio 0.21 found in controls. Furthermore, by subdividing the patients into groups with asthma/rhinitis or different severities of eczema no significant differences in the IF/S-IgE ratios were found compared with the controls. In the controls the IF/S-IgE ratio (0.21) was significantly different from the IF/S-IgG ratio (0.32). The median ratio of IF/S-IgE divided by IF/S-IgG was 0.63, which might indicate a reduced passage of IgE into IF compared with IgG presumably dependent on differences in the molecular size or tertiary structure of the proteins.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Allergic diseases</subject><subject>Biological and medical sciences</subject><subject>Dermatitis, Atopic - immunology</subject><subject>Extracellular Space - analysis</subject><subject>Extracellular Space - immunology</subject><subject>Female</subject><subject>Humans</subject><subject>Immunoglobulin E - analysis</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Skin allergic diseases. Stinging insect allergies</subject><issn>0001-5555</issn><issn>1651-2057</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkLtPwzAQxi0EKqWwsyB5QGwBX_xqEAuqClSqxAJz5PoBRklTbGfof4-jRh245XT6fff6ELoGcl9SRh4IIcBzCMmkYHNygqYgOBQl4fIUTQdcDPwcXcT4k8uSw3yCJiXjQCVM0dPqa4n9FqvU7bzGxoZWJZ98fMQKx9SbPe4cTt82i5IN2jZN36iAXdN7c4nOnGqivRrzDH2-LD8Wb8X6_XW1eF4XmgqeCimcoRutNaOUgQFDHQXghJXaaFWaSjBpQTKjCDMSQNmMKkctlxs-54TO0N1h7i50v72NqW59HE5RW9v1sZayqiA_l4XkINShizFYV--Cb1XY10DqwbD6v2G55Wac3W9aa44No0OZ345cRa0aF9RW-3iUSUHybkH_ADS-cEQ</recordid><startdate>19870101</startdate><enddate>19870101</enddate><creator>BECK, H.-I</creator><creator>HAGDRUP, H. 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K</creatorcontrib><creatorcontrib>BRANDRUP, F</creatorcontrib><creatorcontrib>BONNEVIE-NIELSEN, V</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta dermato-venereologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BECK, H.-I</au><au>HAGDRUP, H. 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In the controls the IF/S-IgE ratio (0.21) was significantly different from the IF/S-IgG ratio (0.32). The median ratio of IF/S-IgE divided by IF/S-IgG was 0.63, which might indicate a reduced passage of IgE into IF compared with IgG presumably dependent on differences in the molecular size or tertiary structure of the proteins.</abstract><cop>Uppsala</cop><pub>Acta dermato-venereologica</pub><pmid>2451371</pmid><doi>10.2340/0001555567476480</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Acta dermato-venereologica, 1987-01, Vol.67 (6), p.476-480 |
| issn | 0001-5555 1651-2057 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Adult Aged Allergic diseases Biological and medical sciences Dermatitis, Atopic - immunology Extracellular Space - analysis Extracellular Space - immunology Female Humans Immunoglobulin E - analysis Immunopathology Male Medical sciences Middle Aged Skin allergic diseases. Stinging insect allergies |
| title | IgE in atopic dermatitis: a study of the intercellular fluid |
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