Molecular Cloning and Expression of Receptor Peptides That Block Human Cytomegalovirus/Cell Fusion

Clones expressing a partial human cytomegalovirus putative fusion receptor were selected by binding specifically to monoclonal anti-idiotypic antibodies that mimic glycoprotein H. cDNA was isolated from 2 of the clones (131 and 611) and fused in frame with the glutathione S-transferase gene in a pGE...

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Veröffentlicht in:	Biochemical and biophysical research communications 1996-02, Vol.219 (2), p.668-673
Hauptverfasser:	Baldwin, Brenda R., Kleinberg, Michael, Keay, Susan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Anti-Idiotypic - pharmacology Antibodies, Monoclonal Blotting, Western Cell Fusion Cells, Cultured Cloning, Molecular Cytomegalovirus - physiology Gene Expression Glutathione Transferase - biosynthesis Humans Lung Membrane Proteins - drug effects Membrane Proteins - physiology Peptide Fragments - biosynthesis Peptide Fragments - pharmacology Receptors, Virus - drug effects Receptors, Virus - physiology Recombinant Fusion Proteins - biosynthesis Recombinant Fusion Proteins - drug effects Recombinant Fusion Proteins - metabolism Viral Plaque Assay
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