Prevention of Attachment of Phosphorylcholine to a Major Excretory-Secretory Product of Acanthocheilonema viteae Using Tunicamycin

ES-62, a major excretory-secretory (ES) product of Acanthocheilonema viteae, consists of a protein backbone with N-linked carbohydrate and the immunomodulatory group phosphorylcholine (PC); it can, therefore, be biosynthetically labeled with radioactive leucine, glucosamine, or choline. Incubation o...

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Veröffentlicht in:	The Journal of parasitology 1996-04, Vol.82 (2), p.320-324
Hauptverfasser:	Houston, Katrina M., Harnett, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Antibodies Antiparasitic agents Biological and medical sciences Blotting, Western Dipetalonema - drug effects Dipetalonema - metabolism Dose-Response Relationship, Drug Electrophoresis, Polyacrylamide Gel Female Gerbillinae Glycoproteins - metabolism Glycosylation - drug effects Helminth Proteins - biosynthesis Helminth Proteins - metabolism Medical sciences Molecular weight Molecules Parasitology Pharmacology. Drug treatments Phosphorylcholine - metabolism Polysaccharides Protein synthesis Radioactive decay Secretion Therapeutics-Diagnostics Tunicamycin - pharmacology Western blotting
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