Traumatic Hypothermia Is Related to Hypotension, Not Resuscitation

Study objective: To determine whether posttraumatic hypothermia is associated with hemorrhage or with resuscitation. Methods: We used a sequential hemorrhage-resuscitation rat model. Rats were subjected to hemorrhage (30 mL/kg), then 1 hour of shock, followed by 2:1 crystalloid/blood resuscitation (...

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Veröffentlicht in:	Annals of emergency medicine 1996, Vol.27 (1), p.39-42
Hauptverfasser:	Bergstein, Jack M, Slakey, Douglas P, Wallace, James R, Gottlieb, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Blood Pressure Body Temperature Disease Models, Animal Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Hypothermia - etiology Intensive care medicine Linear Models Male Medical sciences Rats Rats, Sprague-Dawley Resuscitation - adverse effects Shock, Hemorrhagic - complications Shock, Hemorrhagic - mortality Shock, Hemorrhagic - therapy Wounds and Injuries - complications
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Zusammenfassung:	Study objective: To determine whether posttraumatic hypothermia is associated with hemorrhage or with resuscitation. Methods: We used a sequential hemorrhage-resuscitation rat model. Rats were subjected to hemorrhage (30 mL/kg), then 1 hour of shock, followed by 2:1 crystalloid/blood resuscitation (60 mL/kg) at ambient temperature. A control group underwent neither hemorrhage nor resuscitation. Results: We recorded core temperature and blood pressure every 10 minutes. Temperature drop averaged 3.4°C and was fastest during hypotensive shock. Rate of temperature change correlated with blood pressure (β=.0102, P
ISSN:	0196-0644 1097-6760
DOI:	10.1016/S0196-0644(96)70294-9