Characterization of the Active Intermediate of a GroEL–GroES-Mediated Protein Folding Reaction

Recent studies of GroE-mediated protein folding indicate that substrate proteins are productively released from a cis ternary complex in which the nonnative substrate is sequestered within the GroEL channel underneath GroES. Here, we examine whether protein folding can occur in this space. Stopped-f...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell 1996-02, Vol.84 (3), p.481-490
Hauptverfasser:	Weissman, Jonathan S, Rye, Hays S, Fenton, Wayne A, Beechem, Joseph M, Horwich, Arthur L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Cattle Chaperonin 10 - chemistry Chaperonin 10 - genetics Chaperonin 10 - metabolism Chaperonin 60 - chemistry Chaperonin 60 - genetics Chaperonin 60 - metabolism Escherichia coli - genetics Hydrolysis In Vitro Techniques Kinetics Macromolecular Substances Mutation Protein Folding Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism Thiosulfate Sulfurtransferase - chemistry Thiosulfate Sulfurtransferase - genetics Thiosulfate Sulfurtransferase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!