Cloning and characterization of the thyroid iodide transporter

IODIDE (I - ) is an essential constituent of the thyroid hormones T 3 and T 4 , and is accumulated by the thyroid. The transport of iodide, the first step in thyroid hormogenesis, is catalysed by the Na + /I - symporter, an intrinsic membrane protein that is crucial for the evaluation, diagnosis and...

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Veröffentlicht in:	Nature (London) 1996-02, Vol.379 (6564), p.458-460
Hauptverfasser:	Dai, Ge, Levy, Orlie, Carrasco, Nancy
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Binding and carrier proteins Biological and medical sciences Carrier Proteins - genetics Carrier Proteins - metabolism Cell Line Cloning Cloning, Molecular Deoxyribonucleic acid DNA DNA, Complementary Fundamental and applied biological sciences. Psychology Hormones Humanities and Social Sciences Iodides letter Membrane Proteins - genetics Membrane Proteins - metabolism Molecular Sequence Data multidisciplinary Perchlorate Proteins Science Science (multidisciplinary) Symporters Thyroid Thyroid gland Thyroid Gland - metabolism Xenopus laevis
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