Triiodothyronine Exerts a Major Pleiotropic Effect on Reverse Cholesterol Transport Phenotypes

The thyroid hormone triiodothyronine (T3) is known to be a potent mediator of APOA1 gene expression. With the use of multivariate quantitative genetic analysis, we have assessed the magnitude of shared effects of T3 on plasma concentrations of apolipoprotein AI (apo AI) and three related phenotypesH...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 1996-02, Vol.16 (2), p.289-293
Hauptverfasser:	Comuzzie, Anthony G, Blangero, J, Mahaney, Michael C, Sharp, R. Mark, VandeBerg, John L, Stern, Michael P, MacCluer, Jean W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Apolipoprotein A-I - blood Apolipoprotein A-II - blood Biological Transport Cholesterol - genetics Cholesterol - metabolism Cholesterol, HDL - blood Female Humans Lipoprotein(a) - analogs & derivatives Lipoprotein(a) - blood Male Middle Aged Multivariate Analysis Osmolar Concentration Phenotype Sex Characteristics Triiodothyronine - pharmacology
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