A Chinese hamster ovary cell histone deacetylase that is associated with a unique class of mononucleosomes

The chromatin-bound histone deacetylase of Chinese hamster ovary cells has been studied by using as a substrate an acetylated amino-terminal peptide of histone H4. These studies demonstrate that histone deacetylase activity is associated with mononucleosomes solubilized by digestion with micrococcal...

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Veröffentlicht in:	Biochemistry (Easton) 1987-12, Vol.26 (25), p.8257-8262
Hauptverfasser:	Mold, David E, McCarty, Kenneth S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amidohydrolases - metabolism Animals Biological and medical sciences Cell Fractionation Cell Line Centrifugation, Density Gradient - methods Chromatin - enzymology Chromatin. Chromosome Cricetinae Cricetulus Female Fundamental and applied biological sciences. Psychology Histone Deacetylases - metabolism Molecular and cellular biology Molecular genetics Nucleosomes - metabolism Nucleosomes - ultrastructure Ovary
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