Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor

High density lipoprotein (HDL) and low density lipoprotein (LDL) are cholesterol transport particles whose plasma concentrations are directly (LDL) and inversely (HDL) correlated with risk for atherosclerosis. LDL catabolism involves cellular uptake and degradation of the entire particle by a well-c...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1996-01, Vol.271 (5248), p.518-520
Hauptverfasser:	Acton, Susan, Rigotti, Attilio, Landschulz, Katherine T., Xu, Shangzhe, Hobbs, Helen H., Krieger, Monty
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Glands - metabolism Animals Biological and medical sciences Carrier Proteins CD36 Antigens - genetics CD36 Antigens - metabolism Cell lines Cell receptors Cell regulation Cell structures and functions Cellular biology Cellular control mechanisms CHO Cells Cholesterol Cholesterol - metabolism Cholesterol Esters - metabolism Cholesterols COS cells Cricetinae Death Female Fluorescent Dyes - metabolism Fundamental and applied biological sciences. Psychology HDL lipoproteins Hepatocytes High density lipoproteins Lipids Lipoproteins, HDL - metabolism Liver Liver - metabolism Membrane Proteins Mice Miscellaneous Molecular and cellular biology Molecular Sequence Data Ovaries Ovary - metabolism Proteins Receptors Receptors, Immunologic Receptors, LDL - metabolism Receptors, Lipoprotein - metabolism Receptors, Scavenger RNA-Binding Proteins Scavenger Receptors, Class B Thiazines - metabolism Transfection
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