CYP2D6 genotypes in Spanish women with breast cancer

Wild type and three mutated alleles of the polymorphic CYP2D6 gene were studied in genomic DNA samples from 187 women with breast carcinoma and 151 healthy women by a mutation-specific polymerase chain reaction. The prevalence of the enzyme-inactivating CYP2D6(B) allele was higher among patients (18...

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Veröffentlicht in:	Cancer letters 1996-01, Vol.99 (1), p.23-28
Hauptverfasser:	Ladona, Margarita G., Abildúa, Rosa E., Ladero, JoséM., Román, JoséM., Plaza, María A., Agúndez, JoséA.G., Muñoz, Juan J., Beníez, Julio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Alleles Biological and medical sciences Breast cancer Breast Neoplasms - enzymology Breast Neoplasms - genetics CYP2D6 Cytochrome P-450 CYP2D6 Cytochrome P-450 Enzyme System - genetics Debrisoquine Female Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Middle Aged Mixed Function Oxygenases - genetics P4502D6 Polymorphism Polymorphism, Genetic Spain Tumors
Online-Zugang:	Volltext
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