Activation of alveolar macrophage TNF and MCP-1 expression in vivo by a synthetic peptide of C-reactive protein

Administration of multilamellar vesicles (MLV) encapsulating a synthetic peptide (RS‐83277) derived from human C‐reactive protein (CRP) augments anti‐tumor activity of murine alveolar macrophages and reduces established pulmonary metastases of experimental tumors. To explore mechanisms involved in t...

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Veröffentlicht in:	Journal of leukocyte biology 1996-03, Vol.59 (3), p.397-402
Hauptverfasser:	Barna, Barbara P., Thomassen, Mary Jane, Zhou, Ping, Pettay, James, Singh‐Burgess, Sugatha, Deodhar, Sharad D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Bronchoalveolar Lavage Fluid - cytology C-Reactive Protein - chemistry C-Reactive Protein - pharmacology Chemokine CCL2 - metabolism Chemokines - genetics Cytokines - genetics Gene Expression Immunologic Factors - pharmacology integrin Macrophage Activation Macrophages, Alveolar - immunology Male Mice Mice, Inbred C57BL Molecular Sequence Data monocyte chemoattractant protein 1 Peptide Fragments - pharmacology Peptides - pharmacology RNA, Messenger - genetics tumor necrosis factor Tumor Necrosis Factor-alpha - metabolism
Online-Zugang:	Volltext
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