Retinol Binding Protein and Transthyretin Are Secreted as a Complex Formed in the Endoplasmic Reticulum in HepG2 Human Hepatocarcinoma Cells

Retinol binding protein (RBP), the retinol-specific carrier, circulates in blood as a 1:1 complex with the homotetrameric protein transthyretin (TTR). Both RBP and TTR are synthesized and secreted by the hepatocyte. In this work we have demonstrated, using HepG2 cells as a model system, that the ass...

Ausführliche Beschreibung