Tobacco smoking induces expression of very-high-affinity nicotine binding sites on blood polymorphonuclear cells

The targets of nicotine in the central nervous system (CNS) have been identified as nicotinic acetylcholine (ACh) receptors. Because of their localization in the brain, no data are available about their in vivo modifications. However, nonneuronal nicotine binding sites have been identified on periph...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1996-03, Vol.153 (3), p.1056-1063
Hauptverfasser:	LEBARGY, F, KHALID BENHAMMOU, MORIN, D, ZINI, R, URIEN, S, BREE, F, BIGNON, J, BRANELLEC, A, LAGRUE, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Binding Sites Biological and medical sciences Female Gene Expression Regulation Humans Male Medical sciences Middle Aged Nicotine - metabolism Nicotine - pharmacology Receptors, Nicotinic - genetics Receptors, Nicotinic - metabolism Recurrence Smoking - genetics Smoking - metabolism Smoking Cessation Time Factors Tobacco, tobacco smoking Toxicology Tritium
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