Effects of Subtle Changes in the SU Protein of Ecotropic Murine Leukemia Virus on Its Brain Capillary Endothelial Cell Tropism and Interference Properties

PVC-211 murine leukemia virus (MuLV) is a neuropathogenic variant of Friend MuLV (F-MuLV) that causes a rapidly progressive neurodegenerative disease in susceptible rodents. PVC-211 MuLV, but not the parental F-MuLV, can infect rat brain capillary endothelial cells (BCEC) efficiently, and the major...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1996-01, Vol.215 (2), p.142-151
Hauptverfasser:	MASUDA, MARI, HANSON, CHARLOTTE A., ALVORD, W.GREGORY, HOFFMAN, PAUL M., RUSCETTI, SANDRA K., MASUDA, MICHIAKI
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Amino Acid Sequence Animals Base Sequence Brain - virology Cell Line DNA, Viral Endothelium, Vascular - virology Fibroblasts - cytology Friend murine leukemia virus - chemistry Friend murine leukemia virus - genetics Friend murine leukemia virus - physiology Genetic Vectors Mice Molecular Sequence Data murine leukemia virus Proviruses - genetics Rats Receptors, Virus - metabolism Recombination, Genetic Retroviridae Proteins, Oncogenic - chemistry Retroviridae Proteins, Oncogenic - genetics Retroviridae Proteins, Oncogenic - physiology Structure-Activity Relationship Transduction, Genetic Viral Envelope Proteins - chemistry Viral Envelope Proteins - genetics Viral Envelope Proteins - physiology Viral Interference Virus Integration
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