Salsalate, morphine, and postoperative ileus

Previously, we demonstrated that ketorolac, a nonsteroidal antilnflammatory drug (NSAID), prevented postoperative small bowel ileus in a rodent model. The aim of this study was to evaluate the effect of salsalate, an NSAID without antlplatelet effect, on postoperative ileus alone or in combination w...

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Veröffentlicht in:	The American journal of surgery 1996, Vol.171 (1), p.85-89
Hauptverfasser:	Cheng, Guozhang, Cassissi, Christopher, Drexler, P. Greg, Vogel, Stephen B., Sninsky, Charles A., Hocking, Michael P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Catheters Drug Therapy, Combination Gastrointestinal Motility - drug effects Intestinal Obstruction - drug therapy Intestine Jejunum Laparotomy Male Medical instruments Morphine Morphine - administration & dosage Myoelectricity Nonsteroidal anti-inflammatory drugs Postoperative Complications - drug therapy Postoperative period Rats Rats, Sprague-Dawley Rodents Salicylates - administration & dosage Salicylates - therapeutic use Small intestine Transit Variance analysis
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