Angiogenesis and the skin: A primer
Angiogenesis is the development of a blood supply to a given area of tissue. This area of tissue may be part of normal embryonic development, revascularization of a wound bed, or the stimulation of vessel growth by inflammatory or malignant cells. Angiogenesis is of crucial importance to the dermato...
Gespeichert in:
| Veröffentlicht in: | Journal of the American Academy of Dermatology 1996-03, Vol.34 (3), p.486-497 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 497 |
|---|---|
| container_issue | 3 |
| container_start_page | 486 |
| container_title | Journal of the American Academy of Dermatology |
| container_volume | 34 |
| creator | Arbiser, Jack L |
| description | Angiogenesis is the development of a blood supply to a given area of tissue. This area of tissue may be part of normal embryonic development, revascularization of a wound bed, or the stimulation of vessel growth by inflammatory or malignant cells. Angiogenesis is of crucial importance to the dermatologist, as it is of key importance in pathologic processes such as psoriasis, warts, and cutaneous malignancy, and it is required for optimal wound healing. Other dermatologic processes wherein angiogenesis is defective or uncontrolled are decubitus ulcers, stasis ulcers, pyogenic granulomas, hemangiomas, Kaposi's sarcoma, and possibly Spitz nevus, hypertrophic scars, and keloids. Recent advances in the understanding of growth factors will likely lead to advances in the treatment of skin cancer and psoriasis, and more rapid healing of wounds. In this review, I hope to summarize the most important growth factors, inhibitors of angiogenesis, and future directions in research and therapeutics involving angiogenesis. |
| doi_str_mv | 10.1016/S0190-9622(96)90444-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_77964955</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0190962296904442</els_id><sourcerecordid>77964955</sourcerecordid><originalsourceid>FETCH-LOGICAL-c418t-bdc6d966dde39eef401a6a5d9c6912e66429295a859e0880a0e0ec79226b1a663</originalsourceid><addsrcrecordid>eNqFkEtLAzEQgIMotVZ_QmFBET2sTrLZ7I4XKcUXFDyo55AmszXa7mqyFfz3bh_06mXmMN-8PsaGHK44cHX9AhwhRSXEBapLBCllKvZYnwMWqSrKYp_1d8ghO4rxAwBQZkWP9UoFKJTss9NRPfPNjGqKPiamdkn7Tkn89PVNMkq-gl9QOGYHlZlHOtnmAXu7v3sdP6aT54en8WiSWsnLNp06qxwq5RxlSFRJ4EaZ3KFVyAUpJQUKzE2ZI0FZggECsgUKoaYdqbIBO9_M_QrN95Jiqxc-WprPTU3NMuqiQCUxzzsw34A2NDEGqvTqUBN-NQe9kqPXcvTq8y7otRwtur7hdsFyuiC369ra6Opn27qJ1syrYGrr4w7LIMtKWXTY7QajTsaPp6Cj9VRbcj6QbbVr_D-H_AGjX34q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77964955</pqid></control><display><type>article</type><title>Angiogenesis and the skin: A primer</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Arbiser, Jack L</creator><creatorcontrib>Arbiser, Jack L</creatorcontrib><description>Angiogenesis is the development of a blood supply to a given area of tissue. This area of tissue may be part of normal embryonic development, revascularization of a wound bed, or the stimulation of vessel growth by inflammatory or malignant cells. Angiogenesis is of crucial importance to the dermatologist, as it is of key importance in pathologic processes such as psoriasis, warts, and cutaneous malignancy, and it is required for optimal wound healing. Other dermatologic processes wherein angiogenesis is defective or uncontrolled are decubitus ulcers, stasis ulcers, pyogenic granulomas, hemangiomas, Kaposi's sarcoma, and possibly Spitz nevus, hypertrophic scars, and keloids. Recent advances in the understanding of growth factors will likely lead to advances in the treatment of skin cancer and psoriasis, and more rapid healing of wounds. In this review, I hope to summarize the most important growth factors, inhibitors of angiogenesis, and future directions in research and therapeutics involving angiogenesis.</description><identifier>ISSN: 0190-9622</identifier><identifier>EISSN: 1097-6787</identifier><identifier>DOI: 10.1016/S0190-9622(96)90444-2</identifier><identifier>PMID: 8609264</identifier><identifier>CODEN: JAADDB</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Animals ; Biological and medical sciences ; Dermatology ; Growth Substances - physiology ; Growth Substances - therapeutic use ; Humans ; Medical sciences ; Neovascularization, Pathologic - pathology ; Neovascularization, Physiologic ; Psoriasis - drug therapy ; Psoriasis - pathology ; Skin - blood supply ; Skin Diseases - pathology ; Skin involvement in other diseases. Miscellaneous. General aspects ; Skin Neoplasms - blood supply ; Skin Neoplasms - drug therapy ; Wound Healing</subject><ispartof>Journal of the American Academy of Dermatology, 1996-03, Vol.34 (3), p.486-497</ispartof><rights>1996</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c418t-bdc6d966dde39eef401a6a5d9c6912e66429295a859e0880a0e0ec79226b1a663</citedby><cites>FETCH-LOGICAL-c418t-bdc6d966dde39eef401a6a5d9c6912e66429295a859e0880a0e0ec79226b1a663</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0190962296904442$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>313,314,776,780,788,3537,27899,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3033847$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8609264$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arbiser, Jack L</creatorcontrib><title>Angiogenesis and the skin: A primer</title><title>Journal of the American Academy of Dermatology</title><addtitle>J Am Acad Dermatol</addtitle><description>Angiogenesis is the development of a blood supply to a given area of tissue. This area of tissue may be part of normal embryonic development, revascularization of a wound bed, or the stimulation of vessel growth by inflammatory or malignant cells. Angiogenesis is of crucial importance to the dermatologist, as it is of key importance in pathologic processes such as psoriasis, warts, and cutaneous malignancy, and it is required for optimal wound healing. Other dermatologic processes wherein angiogenesis is defective or uncontrolled are decubitus ulcers, stasis ulcers, pyogenic granulomas, hemangiomas, Kaposi's sarcoma, and possibly Spitz nevus, hypertrophic scars, and keloids. Recent advances in the understanding of growth factors will likely lead to advances in the treatment of skin cancer and psoriasis, and more rapid healing of wounds. In this review, I hope to summarize the most important growth factors, inhibitors of angiogenesis, and future directions in research and therapeutics involving angiogenesis.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Growth Substances - physiology</subject><subject>Growth Substances - therapeutic use</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Neovascularization, Pathologic - pathology</subject><subject>Neovascularization, Physiologic</subject><subject>Psoriasis - drug therapy</subject><subject>Psoriasis - pathology</subject><subject>Skin - blood supply</subject><subject>Skin Diseases - pathology</subject><subject>Skin involvement in other diseases. Miscellaneous. General aspects</subject><subject>Skin Neoplasms - blood supply</subject><subject>Skin Neoplasms - drug therapy</subject><subject>Wound Healing</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEQgIMotVZ_QmFBET2sTrLZ7I4XKcUXFDyo55AmszXa7mqyFfz3bh_06mXmMN-8PsaGHK44cHX9AhwhRSXEBapLBCllKvZYnwMWqSrKYp_1d8ghO4rxAwBQZkWP9UoFKJTss9NRPfPNjGqKPiamdkn7Tkn89PVNMkq-gl9QOGYHlZlHOtnmAXu7v3sdP6aT54en8WiSWsnLNp06qxwq5RxlSFRJ4EaZ3KFVyAUpJQUKzE2ZI0FZggECsgUKoaYdqbIBO9_M_QrN95Jiqxc-WprPTU3NMuqiQCUxzzsw34A2NDEGqvTqUBN-NQe9kqPXcvTq8y7otRwtur7hdsFyuiC369ra6Opn27qJ1syrYGrr4w7LIMtKWXTY7QajTsaPp6Cj9VRbcj6QbbVr_D-H_AGjX34q</recordid><startdate>19960301</startdate><enddate>19960301</enddate><creator>Arbiser, Jack L</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19960301</creationdate><title>Angiogenesis and the skin: A primer</title><author>Arbiser, Jack L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c418t-bdc6d966dde39eef401a6a5d9c6912e66429295a859e0880a0e0ec79226b1a663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Growth Substances - physiology</topic><topic>Growth Substances - therapeutic use</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Neovascularization, Pathologic - pathology</topic><topic>Neovascularization, Physiologic</topic><topic>Psoriasis - drug therapy</topic><topic>Psoriasis - pathology</topic><topic>Skin - blood supply</topic><topic>Skin Diseases - pathology</topic><topic>Skin involvement in other diseases. Miscellaneous. General aspects</topic><topic>Skin Neoplasms - blood supply</topic><topic>Skin Neoplasms - drug therapy</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arbiser, Jack L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arbiser, Jack L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Angiogenesis and the skin: A primer</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>1996-03-01</date><risdate>1996</risdate><volume>34</volume><issue>3</issue><spage>486</spage><epage>497</epage><pages>486-497</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Angiogenesis is the development of a blood supply to a given area of tissue. This area of tissue may be part of normal embryonic development, revascularization of a wound bed, or the stimulation of vessel growth by inflammatory or malignant cells. Angiogenesis is of crucial importance to the dermatologist, as it is of key importance in pathologic processes such as psoriasis, warts, and cutaneous malignancy, and it is required for optimal wound healing. Other dermatologic processes wherein angiogenesis is defective or uncontrolled are decubitus ulcers, stasis ulcers, pyogenic granulomas, hemangiomas, Kaposi's sarcoma, and possibly Spitz nevus, hypertrophic scars, and keloids. Recent advances in the understanding of growth factors will likely lead to advances in the treatment of skin cancer and psoriasis, and more rapid healing of wounds. In this review, I hope to summarize the most important growth factors, inhibitors of angiogenesis, and future directions in research and therapeutics involving angiogenesis.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>8609264</pmid><doi>10.1016/S0190-9622(96)90444-2</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0190-9622 |
| ispartof | Journal of the American Academy of Dermatology, 1996-03, Vol.34 (3), p.486-497 |
| issn | 0190-9622 1097-6787 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77964955 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Biological and medical sciences Dermatology Growth Substances - physiology Growth Substances - therapeutic use Humans Medical sciences Neovascularization, Pathologic - pathology Neovascularization, Physiologic Psoriasis - drug therapy Psoriasis - pathology Skin - blood supply Skin Diseases - pathology Skin involvement in other diseases. Miscellaneous. General aspects Skin Neoplasms - blood supply Skin Neoplasms - drug therapy Wound Healing |
| title | Angiogenesis and the skin: A primer |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T12%3A49%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Angiogenesis%20and%20the%20skin:%20A%20primer&rft.jtitle=Journal%20of%20the%20American%20Academy%20of%20Dermatology&rft.au=Arbiser,%20Jack%20L&rft.date=1996-03-01&rft.volume=34&rft.issue=3&rft.spage=486&rft.epage=497&rft.pages=486-497&rft.issn=0190-9622&rft.eissn=1097-6787&rft.coden=JAADDB&rft_id=info:doi/10.1016/S0190-9622(96)90444-2&rft_dat=%3Cproquest_cross%3E77964955%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77964955&rft_id=info:pmid/8609264&rft_els_id=S0190962296904442&rfr_iscdi=true |