Sensitization of cells and retroviruses to human serum by (αl-3) galactosyltransferase

MAMMALIAN C-type retroviruses are inactivated by human serum 1,2 , following triggering of the classical complement cascade 3 . This may have inhibited transmission to humans of C-type oncoviruses from other mammals 1 . Indeed, the retro-viruses human immunodeficiency virus and human T-cell leukaemi...

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Veröffentlicht in:	Nature (London) 1996-01, Vol.379 (6560), p.85-88
Hauptverfasser:	Takeuchi, Yasuhiro, Porter, Colin D, Strahan, Karen M, Preece, Andrew F, Gustafsson, Kenth, Cosset, Francois-Loic, Weiss, Robin A, Collins, Mary K. L
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells AIDS/HIV Animals Antibodies - immunology Biological and medical sciences Carbohydrate Sequence Carbohydrates Cell Line Cellular biology Dogs Fundamental and applied biological sciences. Psychology Galactose - metabolism Galactosyltransferases - antagonists & inhibitors Galactosyltransferases - blood Galactosyltransferases - metabolism Humanities and Social Sciences Humans Immunity (Disease) Inactivation letter Leukemia Leukemia Virus, Murine - metabolism Mammals Mice Microbiology Molecular Sequence Data multidisciplinary Proteins Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Retroviridae - metabolism Science Science (multidisciplinary) Swine Virology Viruses
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