Detection of excessive bronchoconstriction in asthma

Airway hyperresponsiveness is easily assessed by measuring the concentration or dose of an inhaled agonist that produces a defined response, e.g., PC20 or PD20. However, this measure does not assess excessive bronchoconstriction. We report the results of analyzing bronchial dose-response curves by m...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1996-02, Vol.153 (2), p.582-589
Hauptverfasser:	GIBBONS, W. J, ARUNABH SHARMA, LOUGHEED, D, MACKLEM, P. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Asthma - physiopathology Biological and medical sciences Bronchial Hyperreactivity - physiopathology Bronchial Provocation Tests Bronchoconstriction - drug effects Chronic obstructive pulmonary disease, asthma Dose-Response Relationship, Drug Female Forced Expiratory Volume - drug effects Histamine - administration & dosage Humans Male Medical sciences Methacholine Chloride - administration & dosage Middle Aged Pneumology Reproducibility of Results Retrospective Studies Spirometry Vital Capacity - drug effects
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