Human IgA monoclonal antibodies specific for a major ragweed pollen antigen

Human hybridoma cell lines secreting IgG specific for the major allergen in the pollen of short ragweed, Amb a I, were established from patients who had been receiving antigen injections for immunotherapy. Recombinant Ig genes were then constructed by cloning the heavy and light chain variable regio...

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Veröffentlicht in:	Bio/Technology 1995-08, Vol.13 (8), p.779-786
Hauptverfasser:	Sun, Lee K., Fung, Michael S.C., Sun, William N.C., Sun, Cecily R.Y., Chang, Wen-I, Chang, Tse Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	adn recombinado adn recombine Agriculture alergenos allergene allergens Allergens - immunology ambrosia Amino Acid Sequence Animals Antibodies, Monoclonal Antibody Specificity anticorps monoclonal anticuerpos monoclonales Antigens - therapeutic use Base Sequence Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Cell Line Feasibility Studies Fundamental and applied biological sciences. Psychology genero humano genre humain Health. Pharmaceutical industry hibridoma Humans hybridomas hybridome Hypersensitivity - therapy Immunoglobulin A - immunology immunoglobuline immunoglobulins Immunotherapy Industrial applications and implications. Economical aspects inmunoglobulina Life Sciences mankind Mice Molecular Sequence Data Monoclonal antibodies polen pollen Pollen - immunology Production of active biomolecules Protein Binding recombinant dna Recombinant Proteins - isolation & purification
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