Measurement of Spontaneous Motor Activity by Using Vibrator Response Method in Rats
To investigate the usefulness of spontaneous motor activity (SMA) measurement using the vibrator response method, the acute effects of drugs on SMA were observed in Sprague-Dawley male rats. There were no significant differences between four devices. Methamphetamine (0.3-1 mg/kg, i.p.) and 1-2 mg/kg...
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| Veröffentlicht in: | Experimental Animals 1987/10/01, Vol.36(4), pp.435-442 |
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| Sprache: | eng ; jpn |
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| container_title | Experimental Animals |
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| creator | ASANO, Yuzo ARIYUKI, Fumio |
| description | To investigate the usefulness of spontaneous motor activity (SMA) measurement using the vibrator response method, the acute effects of drugs on SMA were observed in Sprague-Dawley male rats. There were no significant differences between four devices. Methamphetamine (0.3-1 mg/kg, i.p.) and 1-2 mg/kg (s.c.) of apomorphine increased the SMA, but 0.05-0.2 mg/kg (s.c.) of apomorphine decreased the SMA. Apomorphine at 1-2 mg/kg (s.c.) significantly increased the SMA when the vibrator response method was used as compared with the Animex method. These results suggest that the vibrator response apparatus is useful for the measurement of SMA in rats. |
| doi_str_mv | 10.1538/expanim1978.36.4_435 |
| format | Article |
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These results suggest that the vibrator response apparatus is useful for the measurement of SMA in rats.</description><subject>Animals</subject><subject>Apomorphine - pharmacology</subject><subject>Male</subject><subject>Methamphetamine - pharmacology</subject><subject>Motor Activity - drug effects</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Stereotyped Behavior - drug effects</subject><subject>Vibration</subject><issn>0007-5124</issn><issn>1881-7122</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkF1LwzAUhoMoOtR_oJAr7zpzmjZpLsfQKTgEv25D2p66jH7MJBP37-3sHIJXh8PznpfDQ8gFsDGkPLvGr5VpbQNKZmMuxolOeHpARpBlEEmI40MyYozJKIU4OSHn3i_7lSlgINNjcswTLriUI_I8R-PXDhtsA-0q-rzq2mBa7NaezrvQOTopgv20YUPzDX31tn2nbzZ3Zoue0Pdxj3SOYdGV1Lb0yQR_Ro4qU3s8381T8nJ78zK9ix4eZ_fTyUNUcAEhkjGrVCyU4gJBlCgUzwzjOQgl4gxZnpSAaAolstLw1HAwpVSg8lTFmSn4Kbkaaleu-1ijD7qxvsC6Ht7XUqpEpSD7YDIEC9d577DSK2cb4zYamN7a1H9sai70j83-7HLXv84bLPdHO3c9nw186YN5xz03Ltiixv-lv837RLEwTmPLvwHsWYwX</recordid><startdate>19871001</startdate><enddate>19871001</enddate><creator>ASANO, Yuzo</creator><creator>ARIYUKI, Fumio</creator><general>Japanese Association for Laboratory Animal Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19871001</creationdate><title>Measurement of Spontaneous Motor Activity by Using Vibrator Response Method in Rats</title><author>ASANO, Yuzo ; ARIYUKI, Fumio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-720f9269936e16de6938a03b169628e0b4d1eeac968da35a31ad7919b5928ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>1987</creationdate><topic>Animals</topic><topic>Apomorphine - pharmacology</topic><topic>Male</topic><topic>Methamphetamine - pharmacology</topic><topic>Motor Activity - drug effects</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Stereotyped Behavior - drug effects</topic><topic>Vibration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ASANO, Yuzo</creatorcontrib><creatorcontrib>ARIYUKI, Fumio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental Animals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ASANO, Yuzo</au><au>ARIYUKI, Fumio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Measurement of Spontaneous Motor Activity by Using Vibrator Response Method in Rats</atitle><jtitle>Experimental Animals</jtitle><addtitle>Experimental Animals</addtitle><date>1987-10-01</date><risdate>1987</risdate><volume>36</volume><issue>4</issue><spage>435</spage><epage>442</epage><pages>435-442</pages><issn>0007-5124</issn><eissn>1881-7122</eissn><abstract>To investigate the usefulness of spontaneous motor activity (SMA) measurement using the vibrator response method, the acute effects of drugs on SMA were observed in Sprague-Dawley male rats. There were no significant differences between four devices. Methamphetamine (0.3-1 mg/kg, i.p.) and 1-2 mg/kg (s.c.) of apomorphine increased the SMA, but 0.05-0.2 mg/kg (s.c.) of apomorphine decreased the SMA. Apomorphine at 1-2 mg/kg (s.c.) significantly increased the SMA when the vibrator response method was used as compared with the Animex method. These results suggest that the vibrator response apparatus is useful for the measurement of SMA in rats.</abstract><cop>Japan</cop><pub>Japanese Association for Laboratory Animal Science</pub><pmid>3436377</pmid><doi>10.1538/expanim1978.36.4_435</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Experimental Animals, 1987/10/01, Vol.36(4), pp.435-442 |
| issn | 0007-5124 1881-7122 |
| language | eng ; jpn |
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| source | MEDLINE; J-STAGE |
| subjects | Animals Apomorphine - pharmacology Male Methamphetamine - pharmacology Motor Activity - drug effects Rats Rats, Inbred Strains Stereotyped Behavior - drug effects Vibration |
| title | Measurement of Spontaneous Motor Activity by Using Vibrator Response Method in Rats |
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