Thyroid hormone and retinoic acid induce the synthesis of insulin-like growth factor-binding protein-4 in mouse osteoblastic cells

Thyroid hormone (T3) is a known regulator of the transcription rate of specific genes. By subtractive hybridization of T2-treated osteoblastic cells, differentially expressed messenger RNAs (mRNAs) were enriched in the form of double stranded complementary DNA (cDNA) fragments. Sequencing of a diffe...

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Veröffentlicht in:	Endocrinology (Philadelphia) 1996-01, Vol.137 (1), p.281-286
Hauptverfasser:	Glantschnig, H, Varga, F, Klaushofer, K
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Acids Actinomycin Animals Base Sequence Cell culture Cell Line Cell proliferation Cloning, Molecular Cycloheximide Deoxyribonucleic acid DNA DNA sequencing DNA, Complementary - genetics Gene sequencing Genomics Growth factors Homology Hormones Hybridization Insulin Insulin-Like Growth Factor Binding Protein 4 - biosynthesis Insulin-Like Growth Factor Binding Protein 4 - genetics Insulin-like growth factor-binding protein 4 Insulin-like growth factors Mice Molecular Sequence Data Nucleic Acid Hybridization Osteoblasts Osteoblasts - metabolism Protein Biosynthesis Proteins Retinoic acid RNA, Messenger - metabolism Thyroid Thyroid gland Transcription Tretinoin - pharmacology Triiodothyronine Triiodothyronine - pharmacology
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