Interhemispheric modulation of dopamine receptor interactions in unilateral 6-OHDA rodent model

A critical assumption in the unilateral 6‐hydroxydopamine (6‐OHDA) model is that interactions between the intact and denervated hemispheres do not influence the response to insult. The present study examined this issue by assessing the effects of unilateral substantia nigra 6‐OHDA lesions in rats th...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 1995-12, Vol.21 (4), p.299-311
Hauptverfasser:	Lawler, Cindy P., Gilmore, John H., Watts, Val J., Walker, Q. David, Southerland, Stan B., Cook, Larry L., Mathis, Chet A., Mailman, Richard B.
Format:	Artikel
Sprache:	eng
Schlagworte:	6-hydroxydopamine Animals Caudate Nucleus - metabolism Caudate-putamen Corpus callosum Corpus Callosum - physiology Cyclic AMP - metabolism Cyclic AMP efflux Denervation Dopamine - metabolism Dopamine - pharmacology Dopamine Antagonists - pharmacology Dopamine D1 receptors Dopamine D2 receptors Dopamine-stimulated adenylate cyclase Epidepride Male Oxidopamine - pharmacology Putamen - metabolism Quantitative receptor autoradiography Rats Rats, Sprague-Dawley Receptors, Dopamine D1 - metabolism Receptors, Dopamine D2 - metabolism SCH23982 Sensitization Substantia Nigra - drug effects Substantia Nigra - physiology Sulpiride Sulpiride - pharmacology
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